Protein Alignment RAB10 and Rab6

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_477172.1
• Gene: Rab6 / 34636
• FlyBaseID: FBgn0015797
• Length: 208
• Species: Drosophila melanogaster
• Alignment Length: 194
• Identity: 79/194 - (40%)
• Similarity: 118/194 - (60%)
• Gaps: 15/194 - (7%)

Human    10 FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTI 74
            |||:.:|:..||||.::.||..|:|:.|:.:||||||..||:.|:.:.::||:|||||||||.::
  Fly    13 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSL 77

Human    75 TTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQ 139
            ..||.|.:...::||||||..||...|||:.::......||..||:|||.|:.|||.|...:||:
  Fly    78 IPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDKRQVSTEEGER 142

Human   140 IAREHGIRFFETSAKANINIEKAFLTLA--------------EDILRKTPVKEPNSENVDISSG 189
            .|:|..:.|.||||||..|:::.|..:|              || :::..:|:..:|..|...|
  Fly   143 KAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMDSTENKPSED-MQEVVLKDSPNETKDPEGG 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	75/176 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		7/13 (54%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		10/16 (63%)
Rab6	NP_477172.1	Rab6	13..173	CDD:206654	73/159 (46%)