Protein Alignment RAB10 and Rab21

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_001036321.2
• Gene: Rab21 / 3355163
• FlyBaseID: FBgn0039966
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 72/210 - (34%)
• Similarity: 119/210 - (56%)
• Gaps: 18/210 - (8%)

Human     8 LLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQ-GKKIKLQIWDTAGQERF 71
            |.||.:|:|:..||||.::.|:.:|.||...:||:...|..:.:.|: |::.:|.||||||||||
  Fly    12 LNFKAVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIWDTAGQERF 76

Human    72 HTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGK 136
            |.:...||||:.|.:||||||:..||:.:..|:|.:.:....::..:::|||.|::::|.|...:
  Fly    77 HALGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTDLEEQRAVTHDE 141

Human   137 GEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEP----------------NSENVD 185
            ..|.||..|.::.|||||.|..:.:.|..|.:.:|.:...::|                ||::.:
  Fly   142 ALQYARTVGAQYVETSAKENEGVAELFELLTQLMLEQLSQRQPDASPLRLQNPDTDNLNNSDDSE 206

Human   186 ISSGGGVTGWKSKCC 200
            ....|...|.:| ||
  Fly   207 APDPGDPAGQRS-CC 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	64/165 (39%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		5/13 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		11/16 (69%)
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	62/161 (39%)