Protein Alignment RAB10 and Rab10

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Alignment Length: 205
• Identity: 163/205 - (79%)
• Similarity: 177/205 - (86%)
• Gaps: 7/205 - (3%)

Human     1 MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDT 65
            ||||||||||||||||||||||||:|||||||||.:|||||||||||||||||:|||||||||||
  Fly     1 MAKKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDT 65

Human    66 AGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKR 130
            ||||||||||||||||||||||||||||.||||||.|||||||||||||||:|:|||||||.|||
  Fly    66 AGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKR 130

Human   131 VVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSEN-----VDISSGG 190
            ||.|.:||.|||||||||.|||||:|||||:||..|||.||.||..:| ::||     :|..:..
  Fly   131 VVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRE-SAENQERVIIDRRNQE 194

Human   191 GVTGWKSKCC 200
            ...|: ||||
  Fly   195 KAPGY-SKCC 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	146/165 (88%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		11/13 (85%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		16/16 (100%)
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	146/165 (88%)