Protein Alignment RAB10 and Rab27

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Alignment Length: 168
• Identity: 72/168 - (42%)
• Similarity: 113/168 - (67%)
• Gaps: 5/168 - (2%)

Human    11 KLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGK----KIKLQIWDTAGQERF 71
            :.|::|||||||||:|::::|..|:|.||||:||||:.|.:....:    :|.||||||||||||
  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSRGRRHRIHLQIWDTAGQERF 83

Human    72 HTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHA-NEDVERMLLGNKCDMDDKRVVPKG 135
            .::||::||.|||.:|::|:|:.|||...:.||..:..|| :||.:.:|.|||||:...|||.:.
  Fly    84 RSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRD 148

Human   136 KGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRK 173
            :...:.|.:.:.:.||||....|:::|...|...::.:
  Fly   149 QVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMER 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	72/166 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		8/13 (62%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		11/16 (69%)
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	72/168 (43%)