DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NPFFR2 and Npffr2

DIOPT Version :9

Sequence 1:	NP_001138228.1	Gene:	NPFFR2 / 10886	HGNCID:	4525	Length:	423	Species:	Homo sapiens
Sequence 2:	NP_076470.1	Gene:	Npffr2 / 78964	RGDID:	620168	Length:	417	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	326/419 - (77%)
Similarity:	367/419 - (87%)	Gaps:	3/419 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     4 MNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTV 68
            |.::||:|||.:|..||:.|||:|..||||||||:|||||||.|.|:||.||||||||||:||||
  Rat     1 MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCMVGNTV 65

Human    69 VCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVA 133
            |||:|:||::||||||.||.|||||||||||||||||||||||||||||::||||||||||||||
  Rat    66 VCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVA 130

Human   134 ASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLN 198
            ||||||||||||||:|||||||||||:|||||:|:|||.||||||:|||:||||||||||||||:
  Rat   131 ASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAIMLHVQEEKYYRVRLS 195

Human   199 SQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQE 263
            |.||||.||||||||||||||:||||||||.|||||||||||||.|||.|||:.:...||::..|
  Rat   196 SHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTSAHSTGKQRLE 260

Human   264 QWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGN 328
            ||| ||:||||:|||||.|||||||||||||||||||||||||||:|::||||:|||||||||.|
  Rat   261 QWH-VSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYADLSPNKLRVINIYVYPFAHWLAFCN 324

Human   329 SSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHG 393
            ||||||||||||||||.|||:||  |.|||:.||.|||.|:||.::.||||..||.|...|||.|
  Rat   325 SSVNPIIYGFFNENFRSGFQDAF--QFCQKKVKPQEAYGLRAKRNLDINTSGLLVHEPASQNPSG 387

Human   394 ETLLYRKSAEKPQQELVMEELKETTNSSE 422
            |.|..||||:.|.||.:|||..|.|||:|
  Rat   388 ENLGCRKSADNPTQESLMEETGEATNSTE 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NPFFR2	NP_001138228.1	7tm_4	56..>178	CDD:304433	107/121 (88%)
NPFFR2	NP_001138228.1	7tm_1	65..336	CDD:278431	229/270 (85%)
Npffr2	NP_076470.1	7tm_4	53..>176	CDD:304433	108/122 (89%)
		7tm_1	62..332	CDD:278431	229/270 (85%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..417		22/39 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83697636
Domainoid	1	1.000	478	1.000	Domainoid score	I8000
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56982
Inparanoid	1	1.050	670	1.000	Inparanoid score	I9205
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG44106
OrthoDB	1	1.010	-	-		D106732at9347
OrthoFinder	1	1.000	-	-		FOG0005442
OrthoInspector	1	1.000	-	-		oto134096
orthoMCL	1	0.900	-	-		OOG6_111889
Panther	1	1.100	-	-	LDO	PTHR24241
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X258
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.410