Protein Alignment NPFFR2 and NPFR

DIOPT Version :9

• Sequence 1: NP_001138228.1
• Gene: NPFFR2 / 10886
• HGNCID: 4525
• Length: 423
• Species: Homo sapiens
• Sequence 2: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 378
• Identity: 108/378 - (28%)
• Similarity: 185/378 - (48%)
• Gaps: 60/378 - (15%)

Human    17 HPIWNVN-DTKHHL------YSDINIT--------YVNYYLHQPQVAA----IFIISYFLIFFLC 62
            ||:..:: .|.|.|      .||:|.|        .::.:|....|.:    :.|..|.::....
  Fly    36 HPLDYLDLGTVHALNTTAINTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFG 100

Human    63 MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFG--NTMCKISG 125
            .:|||:|...|:|...|.|..|||||||||||||:.:..||:||::.:...||:|  :.:||...
  Fly   101 ALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIA 165

Human   126 LVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEE 190
            ::|.:.:..|..::.|||.||:|.:|||.:..|....|..|:..||.||:.:.||..|
  Fly   166 MLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFV------- 223

Human   191 KYYRVRLNSQNKT--------SPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMY----- 242
              |:..:|:....        ..:.:|.||||::..|..|:.......||.|:.::.:.|
  Fly   224 --YKELINTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYN 286

Human   243 ---GRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYAD 304
               .||.:...:|:   :.::..|:    .|:.::...:|:.:|::|.:||||   |...:.|||
  Fly   287 KLKSRITVVAVQAS---SAQRKVER----GRRMKRTNCLLISIAIIFGVSWLP---LNFFNLYAD 341

Human   305 LSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQ 357
            :..:.:....:..|...|.:...::..||::||:.|:|||:.|||.    ||:
  Fly   342 MERSPVTQSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQEL----LCR 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFFR2	NP_001138228.1	7tm_4	56..>178	CDD:304433	48/123 (39%)
		7tm_1	65..336	CDD:278431	84/288 (29%)
NPFR	NP_001246947.1	7tm_4	98..>195	CDD:304433	41/96 (43%)
		7tm_1	103..373	CDD:278431	84/288 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3897
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940