DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MRPS30 and mRpS30

DIOPT Version :9

Sequence 1:	NP_057724.2	Gene:	MRPS30 / 10884	HGNCID:	8769	Length:	439	Species:	Homo sapiens
Sequence 2:	NP_001285297.1	Gene:	mRpS30 / 32530	FlyBaseID:	FBgn0030692	Length:	557	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	114/441 - (25%)
Similarity:	177/441 - (40%)	Gaps:	75/441 - (17%)

- Green bases have known domain annotations that are detailed below.

Human    44 YPPIVASMTADSKAARLRRIERWQATVHAAESVDEKLRILTKMQFMKYMVY---PQTFALNADRW 105
            ||.|   .....||.:.:....|...:....:|:||:..:...::..:.|.   ......||...
  Fly    35 YPEI---QDLSFKARKQKDAANWHEEIRQVPTVEEKMIKINMPRYYGFKVVDFNDSKIPYNALPL 96

Human   106 YQYFTKTVFLSGLP---PPPAEPEPEPEPEPEPALD--LAALRAVACDCLLQEHFYLRRRRRVHR 165
            .|::|:|| |..||   ...|:.:...:.:.:|::|  ..|.|....|.|...|.|.:...:.|.
  Fly    97 TQHYTRTV-LEDLPSETDKKAQAKDSEQEQEQPSVDGLFKAARGDVIDALEFAHDYYKHLEKQHN 160

Human   166 YEES------EVISLPFLDQLVSTLVGLLSPHNPALAAAALDYRCPVHFYWVRGEEIIPRG---H 221
            ..||      .:::...::||...|:..||.....|....:||......:|..|....|:.   .
  Fly   161 SAESNPVERERILTQIIVEQLNRALLQSLSEEYKHLDELDVDYNPRHEAFWAVGGVDPPKNVQKS 225

Human   222 RRGR----------IDDLRYQIDDKPNNQIRISKQLAEFVPLDYSVPIEIPTIKCKPDKLPLFKR 276
            ::||          :|.: .|....|...:|..|||..:.....|..:|:      ..:||.||.
  Fly   226 KKGREWQKDMANESVDRM-VQYTGAPYLALRHRKQLTPWKTEAESENLEL------SKQLPRFKH 283

Human   277 QYENHIFVGSKTADPCCYGHT-------------------QFHLLPDKLRRERLLRQNC---ADQ 319
                         ||...|::                   .|.||..:.|....:|...   .||
  Fly   284 -------------DPRTLGYSTKHQHATNVPGYWPKGNENNFGLLSFQSRAHLQIRPKSFGEQDQ 335

Human   320 IEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYFSFFCYQLNTLALTTQAD 384
            :|.: .:.||.|.:||..|||.|.||.:..::|.|..:|.|||:|:.:||:.||||||.|.....
  Fly   336 LEAL-HSLAIKSSYAWLLAQANYNGFNTYNELTYPMNTQTVITNGREWSFYEYQLNTLLLHGTNV 399

Human   385 QNNPRKNICWGTQSKPLYETIE-DNDVKGFNDDVLLQIVHFLLNRPKEEKS 434
            ..|||.|.|.||:..|||..|. ......|||:.|..:::|..|.|..::|
  Fly   400 AENPRVNFCRGTKPLPLYAEISASGKCVDFNDNALRHLLNFYANAPSIQRS 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MRPS30	NP_057724.2	PDCD9	1..426	CDD:399848	111/431 (26%)
mRpS30	NP_001285297.1	PDCD9	6..442	CDD:284543	111/431 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140649
Domainoid	1	1.000	98	1.000	Domainoid score	I7220
eggNOG	1	0.900	-	-		E1_KOG4461
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9607
Inparanoid	1	1.050	100	1.000	Inparanoid score	I5007
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D239149at33208
OrthoFinder	1	1.000	-	-		FOG0006311
OrthoInspector	1	1.000	-	-		oto90743
orthoMCL	1	0.900	-	-		OOG6_108555
Panther	1	1.100	-	-	LDO	PTHR13014
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3573
SonicParanoid	1	1.000	-	-		X5259
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790