DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FGL2 and CG31832

DIOPT Version :9

Sequence 1:	NP_006673.1	Gene:	FGL2 / 10875	HGNCID:	3696	Length:	439	Species:	Homo sapiens
Sequence 2:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster

Alignment Length:	206	Identity:	85/206 - (41%)
Similarity:	119/206 - (57%)	Gaps:	18/206 - (8%)

- Green bases have known domain annotations that are detailed below.

Human   233 PKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKE 297
            |:...|:| ...:|....|.|:|.|||||.||.::|..||.|||:...||::|..|::|:|:.:.
  Fly    39 PEEEPFQV-TQCKTTARDWIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFIGLQKLYLMTREQP 102

Human   298 MILRIDLEDFNGVELYALYDQFYVANEFLKYRL-HVGNYNGTAGDALRFNKHYNHDLKFFTTPDK 361
            ..|.|.|:...|..:||.:|.|.|.:|...|:| .||.|:|||||:||:  |.|   |.|:|.|:
  Fly   103 HELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSGTAGDSLRY--HIN---KRFSTFDR 162

Human   362 DNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFK 426
            |||. .|.||...:..||||.:|||::|||.|:.:...|:.|||.||.|.          ..|..
  Fly   163 DNDE-SSKNCAAEHGGGWWFHSCLSSSLNGLYFREGETGMLNGIHWGRWK----------FQSLT 216

Human   427 EAKMMIRPKHF 437
            ..::|||||:|
  Fly   217 FVQIMIRPKYF 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FGL2	NP_006673.1	DUF460	<28..>161	CDD:331991
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	103..126
		FReD	209..435	CDD:294064	82/202 (41%)
CG31832	NP_723894.2	FReD	28..225	CDD:238040	82/202 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4150
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860