Protein Alignment TSPAN9 and Tsp5D

DIOPT Version :9

• Sequence 1: NP_001161792.1
• Gene: TSPAN9 / 10867
• HGNCID: 21640
• Length: 239
• Species: Homo sapiens
• Sequence 2: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 76/261 - (29%)
• Similarity: 129/261 - (49%)
• Gaps: 31/261 - (11%)

Human     8 CLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGC 72
            |::......|:|.|||.|..||.|:||.:|...:||..|....|||..:.:.||....|..|.||
  Fly     8 CIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSFFGC 72

Human    73 LGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLYHTENNVG---- 133
            .||..:::|||:.:|::::::.::|.::..:.|::...:......:|:.|:..::..::.|
  Fly    73 CGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLVA 137

Human   134 --LKNAWNIIQAEMRCCGVTDYTDWYPVL---GENTVPDRCC---------MENSQG-------C 177
              :.:.|:.:|....||||:.|.|||.:.   |...||:.||         :....|       |
  Fly   138 PSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMMRPDC 202

Human   178 GRNATTPL-WRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHI-HR----TGKK 236
            ||:....| |..||...::.||....:|:|.||:.|..:|:.|:..||.||..: |:    |.|.
  Fly   203 GRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVKHKRASDTYKS 267

Human   237 Y 237
            |
  Fly   268 Y 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN9	NP_001161792.1	Tetraspannin	9..226	CDD:395265	69/242 (29%)
		NET-5_like_LEL	105..202	CDD:239418	29/122 (24%)
Tsp5D	NP_001259266.1	Tetraspannin	8..256	CDD:278750	72/247 (29%)
		NET-5_like_LEL	105..228	CDD:239418	29/122 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	141	1.000	Domainoid score	I4711
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4860
Inparanoid	1	1.050	143	1.000	Inparanoid score	I4462
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1224210at2759
OrthoFinder	1	1.000	-	-		FOG0001172
OrthoInspector	1	1.000	-	-		otm41382
orthoMCL	1	0.900	-	-		OOG6_108304
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6363
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.800