DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SLC22A7 and CG33233

DIOPT Version :9

Sequence 1:	XP_011512558.1	Gene:	SLC22A7 / 10864	HGNCID:	10971	Length:	610	Species:	Homo sapiens
Sequence 2:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	71/306 - (23%)
Similarity:	123/306 - (40%)	Gaps:	75/306 - (24%)

- Green bases have known domain annotations that are detailed below.

Human   176 YSPSWRESLGG----LLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLV 236
            |..|..||:..    :|:..|:|...::|.|   .:.....|::...:..|:|:||:||:.::.:
  Fly    30 YMYSVTESMTAGYLVVLTSCEFDTSPKEKTL---LANSLLGGMVASGLFIGFLADRYGRKFVIRL 91

Human   237 AYVSTLVLGLASAASVSYVMFAITRTLTGSALA-------GFTIIVMPLGEAE-LEWLDVEHRTV 293
            |.|..|...:.||........::.|.:.|:.|:       ||      |||.. ::|..:   ||
  Fly    92 ALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGF------LGEFHAIKWRPI---TV 147

Human   294 A------------------GVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWV 340
            |                  .:|.:.|   .|.|.:  .|.:|.||:|::...:|....::.:..|
  Fly   148 AICSQSQGLALIYCPLVAMAILPNNF---NVDLSS--SYNLRVWRFLMMFFMIPGWLALVGICLV 207

Human   341 PESARWLLTQGHVKEAHRYLLHCARLNGRPVCED-----------SFSQEAVSKVAAGERVVRRP 394
            ||:..:|::.....:|...|....|:| |...||           :..||...|....|
  Fly   208 PETPHFLMSVNRPDKALLALKWICRMN-RKKWEDVDITLSEEKSSTNDQEGFWKTVWYE------ 265

Human   395 SYLDLFRTPRLRHISLCCVVVWFGVNFSYYGL--------SLDVSG 432
             |..||..|.:....:|..:: ||:.|:..||        ::|.||
  Fly   266 -YKLLFSKPHVFKFFICLFLI-FGIFFTSIGLGIWFPVIRNMDNSG 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	71/306 (23%)
SLC22A7	XP_011512558.1	MFS	206..563	CDD:119392	62/272 (23%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	71/306 (23%)
		MFS	23..>208	CDD:119392	43/194 (22%)
		MFS	354..>482	CDD:304372
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840