Protein Alignment SLC26A1 and CG7912

DIOPT Version :10

• Sequence 1: NP_071325.2
• Gene: SLC26A1 / 10861
• HGNCID: 10993
• Length: 701
• Species: Homo sapiens
• Sequence 2: NP_651761.2
• Gene: CG7912 / 43561
• FlyBaseID: FBgn0039736
• Length: 602
• Species: Drosophila melanogaster
• Alignment Length: 651
• Identity: 158/651 - (24%)
• Similarity: 277/651 - (42%)
• Gaps: 132/651 - (20%)

Human    32 KARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGL 96
            |||     ||   |....|...||.|.||.:|: ..:||.||::||.:|:..|||||||..:|.|
  Fly    23 KAR-----SC---CSMRSVHRYLPVTDWLPKYQ-LNFLAMDVVAGLTVGLTAVPQAIAYGAVANL 78

Human    97 QPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSST 161
            .|.|.||::|....:|.|:||.:.::||..:::.|||...||
  Fly    79 PPAYGLYSAFMGGFVYILLGTCKDITVGPTAIMALMVQPYVD----------------------- 120

Human   162 LNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTS 226
                      |...||:.:.    .::|....|||:|.||.:..::|.|:..||.|.|::||.|.
  Fly   121 ----------GNPAYAVLIC----FLSGCIITLMGLLNLGVLMRFISVPVTTGFTMAAALTIATG 171

Human   227 QLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSD--------- 282
            |:..|.|:    .......:.:|:.......|....|.:.....|.:||..::|.:
  Fly   172 QVNSLFGI----SSSASGFLNSWIYFFGHITQTRRNDAILGCCTLVLLLLMRQLKNLTFGFKSVW 232

Human   283 RY----RHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPP---QVPEP----- 335
            :|    |:.:.|     |:.|::..|:.:.|:|......|:...:|...:||   :.||.
  Fly   233 KYISLARNAVAV-----LIGILLCYLLKNDGKLPFLVSGSITPGLPPFKLPPFHTEDPETGETIS 292

Human   336 --RLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAA 398
              .::..|....|::.|::...||::|:.|  |.|..|.|:||::|:|..|:|.:|......:.:
  Fly   293 FGGMVSNVGTALVSIPLLSILESIAVAKAF--SKGKIVDASQEMIALGVSNILSSFFSSMPITGS 355

Human   399 LAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRL 463
            ..::.:..|:|.:|.|...|:..:||:.|..|...|..:.::.||.:|:.:: ..:.:...:..:
  Fly   356 FTRTAINNASGVKTPLGGAVTGALVLMTLAFLTTTFAYIPKATLAAIIIAAM-FFMVEYETIGEI 419

Human   464 WRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEF 528
            ||....|.|.:..|..||:..:.|.|::.|::.:.|.|..::.:|:           |:....:|
  Fly   420 WRAKKRDMLPFLVTVLTCVFWTLEYGMVVGIVFNALFLLYKSMKPQ-----------FFLTTEKF 473

Human   529 EGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDL 593
            .|:    .|.:....|.:.||..::...||.|       .:..|..||.:.|.:   ...:|.::
  Fly   474 NGI----EVTMADLKGSVDYAAAEYLKMSLVS-------HVTQRNSEGSAPTTL---VVIKGHEI 524

Human   594 GPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILS 658
            ..:.|..||                          .|:.||.|...|...::....|.|...::.
  Fly   525 ASIDTTVAL--------------------------NLKSLREDLALLKCDMICWNWSIPAAGVIC 563

Human   659 R 659
            |
  Fly   564 R 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC26A1	NP_071325.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		sulP	55..683	CDD:273284	150/628 (24%)
CG7912	NP_651761.2	SUL1	45..543	CDD:440424	142/598 (24%)