DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC26A1 and Esp

DIOPT Version :10

Sequence 1:NP_071325.2 Gene:SLC26A1 / 10861 HGNCID:10993 Length:701 Species:Homo sapiens
Sequence 2:NP_524490.2 Gene:Esp / 42962 FlyBaseID:FBgn0013953 Length:654 Species:Drosophila melanogaster


Alignment Length:541 Identity:138/541 - (25%)
Similarity:246/541 - (45%) Gaps:105/541 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    45 CVRALVQDL-------------LPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGL 96
            |.|:.:||.             ||...||.:|..:: ..||:::|:.:|:.::|||:||:.:|||
  Fly    63 CTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYNSQD-AVGDLVAGITVGLTVIPQALAYAGIAGL 126

Human    97 QPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSST 161
            ...|.||.||....:|..:|:.:.|.:|..:::.|:..|......|                .|.
  Fly   127 PVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLTYQAAQGSWQ----------------KSV 175

Human   162 LNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTS 226
            |                     |.|::|:.::|||:..|||:..::|.|:..||....|:.||||
  Fly   176 L---------------------LCLLSGIVELLMGLFGLGFLIDFVSGPVSSGFTSAVSLIILTS 219

Human   227 QLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELS---------- 281
            |::.:||:..   :|...|.: |..:..........|.|....|:.:||..:.||          
  Fly   220 QIQSVLGITA---KGNTFVEI-WTQVFHNIEHTRAGDTVLGLTCIVILLLMRSLSSCRIGPVDEK 280

Human   282 -----DRYRHRLR--VPLPTELLVIVVATLVSHFGQLH-KRFGS--SVAGDIPTGFMPPQVPEPR 336
                 .|..:::.  |......:::||..::.:  .|| :..|:  .|.|:||.|....|:|...
  Fly   281 ECSSFQRAVNKILWIVGTARNAILVVVCCIMGY--MLHTEEHGAPFRVVGEIPPGLPSIQLPPTS 343

Human   337 LMQRVALDAVA----------------LALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNV 385
            |......:.||                :.|::...:|::.:.||  :|..|.|:|||:|:|..|:
  Fly   344 LTANETSNGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFA--NGKPVDASQELIAIGTANI 406

Human   386 LPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSL 450
            ..:|:..|..:.||::..|..|:|.||.||::.|..:|::.||.|.|.|:.:.|..||.:|:.::
  Fly   407 FNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFIPRPTLAAIIISAV 471

Human   451 RGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPR--TALL 513
            ...: :|..:..:||...:|.:...||...|:::..|.|:|.||.|:::.:.....||:  |.||
  Fly   472 VFMI-EVKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFILYHAARPKLSTELL 535

Human   514 ARIGDTAFYEDATEFEGLVPE 534
            ..       :...|:..:.|:
  Fly   536 TT-------QSGVEYSMITPD 549

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC26A1NP_071325.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
sulP 55..683 CDD:273284 133/518 (26%)
EspNP_524490.2 SUL1 93..622 CDD:440424 130/511 (25%)
Blue background indicates that the domain is not in the aligned region.

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