Protein Alignment SLC26A1 and CG6125

DIOPT Version :10

• Sequence 1: NP_071325.2
• Gene: SLC26A1 / 10861
• HGNCID: 10993
• Length: 701
• Species: Homo sapiens
• Sequence 2: NP_732032.1
• Gene: CG6125 / 41882
• FlyBaseID: FBgn0038337
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 151/637 - (23%)
• Similarity: 267/637 - (41%)
• Gaps: 155/637 - (24%)

Human    59 WLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSV 123
            |:..| .||....|:::|:.:|:.::||:|||:.||||...|.||::|..::||...||...||:
  Fly    89 WITSY-DREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFFGTIPQVSI 152

Human   124 GIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVATALTLMT 188
            |..||:.::.       ||.....|                             ::|...|..:.
  Fly   153 GPTSLMAILT-------LQFCADKP-----------------------------VQVVIVLAFLA 181

Human   189 GLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLL 253
            ||.::.|||.:|||:.:::..|:...|..|.::.::.:|:|:||||||......|    .:.:.:
  Fly   182 GLVELAMGVFQLGFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVRIKGFPSIG----DFFTNI 242

Human   254 RGAGQANVCDVVTSTVCLAVLLAAKELSD-------RYRHRLR-----VPLPTELLVIVVATLV- 305
            |..      |......|:.|||:.:.||.       ....||:     :.:....||:....|:
  Fly   243 RPT------DAAMGISCMVVLLSLRLLSQVNFKQDTPVTRRLKKILWYISISRNALVVFFTGLLV 301

Human   306 ------SHFGQLHKRFGSSVAGDIPTGFMPPQVPEPR--------LMQRVALDAVALALVAAAFS 356
                  |....:.....|.|:..:||..:||...|.:        ::..:....|.:.:||...:
  Fly   302 FIWVKKSSIEAVPFALSSKVSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVVPIVAVLAN 366

Human   357 ISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSAT 421
            :::|:.|.:..  ::.|:||:|.:|.||:..:|.....|..|..:|.|..|:|.||.::.:.:..
  Fly   367 VAIAKAFVKDG--NLDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGL 429

Human   422 VVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDL---PRLWRMSPADALVWAGTAATCML 483
            :||..|..|.|.|..:.::.|:.|::    .|:..:.||   ..||:.:..|...|.|:...|::
  Fly   430 IVLSALSILTPYFQYIPKASLSAVLI----AAVIFMIDLAPVKELWQTNKKDFFSWVGSFIICLV 490

Human   484 VSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAF-----YEDATEFEGLVPEPGVRVFRFG 543
            ...|.|||.|::||::           .:|.|:|:..|     ..::|.:..:||:..|
  Fly   491 AGVELGLLFGIVLSMV-----------FILLRLGNPKFEVTLKQHESTYYVHIVPQSDV------ 538

Human   544 GPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAG 608
               ||             ||:||                               .|:.|..|...
  Fly   539 ---YY-------------TGVDA-------------------------------LRSELRGACRL 556

Human   609 FHT---VVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDIL 657
            :|.   ||:|||..:..||.....|..:.::..:..:.|:|...|..|:.:|
  Fly   557 YHNDFPVVLDCARFMQFDATFSEMLISVAKEMASHDVLLILQNMSLKVQQML 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC26A1	NP_071325.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		sulP	55..683	CDD:273284	151/637 (24%)
CG6125	NP_732032.1	PRK11660	87..620	CDD:481320	151/637 (24%)