DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC26A1 and CG6928

DIOPT Version :10

Sequence 1:NP_071325.2 Gene:SLC26A1 / 10861 HGNCID:10993 Length:701 Species:Homo sapiens
Sequence 2:NP_648539.1 Gene:CG6928 / 39367 FlyBaseID:FBgn0036240 Length:612 Species:Drosophila melanogaster


Alignment Length:525 Identity:140/525 - (26%)
Similarity:234/525 - (44%) Gaps:94/525 - (17%)


- Green bases have known domain annotations that are detailed below.


Human    53 LLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGT 117
            |||..:||..|..::.:| |:::|:.:|:.::||.:||:.||||:|.|.||::|...:||.::|:
  Fly    10 LLPGLKWLHGYTGQDAVA-DLIAGVTVGLTVLPQGLAYATLAGLEPQYGLYSAFVGGIIYAMLGS 73

Human   118 SRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVAT 182
            .|.|::|..:||.||..       :..||     ||..|                 ..|||    
  Fly    74 CRQVTIGPTALLALMTS-------RHTGF-----GLGSG-----------------PAYAI---- 105

Human   183 ALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGM-VV 246
            .|.|::|:.::.|.||:||.:...:|.|:..||....:|.|.|||||.|||:|    .|.|. .:
  Fly   106 LLCLISGVVELGMAVLKLGALVDLISLPVTVGFTSATAVIIGTSQLKGLLGLR----GGSGSDFI 166

Human   247 LTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSD-RYRHRLRVPLPTELLV------------ 298
            .|..|:.....:....|.......:.|||..::|.| :...|:| .|.|:.||            
  Fly   167 NTMRSVFGNLHKVRTGDFTLGLTSIIVLLLLRKLKDVKLDGRIR-NLRTQQLVSGSIWVIGTGRN 230

Human   299 --IVVATLVSHFGQLHKRFGSS--VAGDIPTGFMPPQVPEPR-------------------LMQR 340
              :|:.|.|..:....:.....  :.|.:.:|.  |.|..|:                   ::..
  Fly   231 ALVVLVTSVLAYSTCEQMESCPFILTGKVKSGL--PNVSLPKFETTILDRNGTEIRQNFEQMLSE 293

Human   341 VALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVK 405
            :....:.|.::|...::::::.|.   |..:...:||:|:...|:..||......:.:.::|.|.
  Fly   294 LGPSMLILPIIAVLGNVAISKAFG---GAGLSPTRELVALSMSNICGAFCSSMPVTGSFSRSAVN 355

Human   406 TATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPAD 470
            .|:|.||.|....::.:|||.|..|||.|..:.::.|:.||:.::...:......| |||.|..:
  Fly   356 HASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAVIFMIEFEVIKP-LWRCSRRE 419

Human   471 ALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTA------------LLARIGDTAFYE 523
            .|..|.|....:.|..|.|||.||...:..|..|..||..:            :|.|...::.|.
  Fly   420 LLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAARPVLSVSKLQTTNGINYILIRPKHSSLYF 484

Human   524 DATEF 528
            .|.|:
  Fly   485 PAVEW 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC26A1NP_071325.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
sulP 55..683 CDD:273284 138/523 (26%)
CG6928NP_648539.1 SUL1 19..540 CDD:440424 135/516 (26%)
Blue background indicates that the domain is not in the aligned region.

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