DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC26A1 and CG5002

DIOPT Version :10

Sequence 1:NP_071325.2 Gene:SLC26A1 / 10861 HGNCID:10993 Length:701 Species:Homo sapiens
Sequence 2:NP_611262.1 Gene:CG5002 / 37025 FlyBaseID:FBgn0034275 Length:595 Species:Drosophila melanogaster


Alignment Length:486 Identity:116/486 - (23%)
Similarity:229/486 - (47%) Gaps:71/486 - (14%)


- Green bases have known domain annotations that are detailed below.


Human    44 LCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFA 108
            ||..:.|.:..|..:||.:|| .||:..|.::|..:|:..:||||||.::|||:|.|.||::|..
  Fly    27 LCRPSTVTNKFPILKWLPRYR-LEYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMG 90

Human   109 NLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGR 173
            ...|.:.|:.:.|::...:::.|||.|.                       :|::...|:|.|  
  Fly    91 CFTYIVFGSCKDVTIATTAIMALMVNQY-----------------------ATISPDYAVLVC-- 130

Human   174 DCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPR 238
                        .:.|...:|:|:|.:|.:..::|.|::.||.|.|:.||.::|:.:::|:..|.
  Fly   131 ------------FLAGCIVLLLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTSPS 183

Human   239 HQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSD-RYRHRL---RVPLPTELLVI 299
            :.    ::..|.:.........:.|.:.....|..||....:.| ::.:|:   .:.|....|.:
  Fly   184 ND----LLPAWKNFFTHLTSIRLWDALLGVSSLVFLLLMTRVKDIKWGNRIFWKYLGLSRNALAV 244

Human   300 VVATLVSHFGQLHKRFGSS---VAGDIPTGFMPPQVPE------------PRLMQRVALDAVALA 349
            :..|.:::   :..|.|:.   |.|:|..|..|.::|.            ..::..|.....::.
  Fly   245 IFGTFLAY---ILSRDGNQPFRVTGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIP 306

Human   350 LVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQL 414
            |::....:::::.|  |.|..|.|:||::|:|.||::.:|:.....:.:..::.|..|:|.:|.|
  Fly   307 LISILEIVAISKAF--SKGKIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPL 369

Human   415 SSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRG--ALRKVWDLPRLWRMSPADALVWAGT 477
            ...|:..:||:.|..|...|:.:.:..||.:|:.::..  .|.|:.|   :|:....|...:..|
  Fly   370 GGAVTGALVLMALAFLTQTFYFIPKCTLAAIIIAAMISLVELHKIKD---MWKSKKKDLFPFVVT 431

Human   478 AATCMLVSTEAGLLAGVILSLLSLAGRTQRP 508
            ..|||..|.|.|:|.|:..:::.:...:.||
  Fly   432 VLTCMFWSLEYGILCGIGANMVYILYSSARP 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC26A1NP_071325.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
sulP 55..683 CDD:273284 113/475 (24%)
CG5002NP_611262.1 SUL1 45..538 CDD:440424 110/468 (24%)
Blue background indicates that the domain is not in the aligned region.

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