Protein Alignment HPSE and CG14309

DIOPT Version :10

• Sequence 1: NP_006656.2
• Gene: HPSE / 10855
• HGNCID: 5164
• Length: 543
• Species: Homo sapiens
• Sequence 2: NP_650718.2
• Gene: CG14309 / 42212
• FlyBaseID: FBgn0038611
• Length: 966
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 78/361 - (21%)
• Similarity: 146/361 - (40%)
• Gaps: 72/361 - (19%)

Human   199 WNSSNAQLLLDYCSSKGY-NISWELGNEPNSFLKKADIFINGSQLGEDFIQLHKLLR--KSTFK- 259
            |:|.:...:|:.....|. :..|:||.:            .|:...:|::|..:.|:  ..|||
  Fly   119 WDSMHTLKILNTSYMVGITDCIWQLGTD------------FGTSRAKDYVQELRTLKLMTDTFKP 171

Human   260 ---NAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYLNGRTATKEDFLNPDVLDIFIS 321
               :.:|.|.|:.  ...:|...|.::....::..:..|         ....:.|....|..::.
  Fly   172 YVDDWRLMGADIS--AGSSADETKRYVDMSKDLNTAFGW---------TQPANMLPKSSLGSYLY 225

Human   322 SVQKVFQVVESTRPGKKVWL---GETSSAYGGGAPLLSDTFAAGFMWLDKLGLSARMGIEVVMRQ 383
            ......:.::..|  ..:||   .|.||     ..|:.|.......|...:|.:|..|.:|:.::
  Fly   226 DSDPALRTLQQQR--VPLWLTLPEERSS-----QRLVGDETTDALRWAQTMGDAAASGFDVIFKR 283

Human   384 VFFGAGNYHLVD---ENFDPLPDYWLSLLFKKLVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRY 445
            :       :|||   .||    ..:::.||||::|::|..|....:.....::|.||.|.
  Fly   284 M-------NLVDFERPNF----SLYVTALFKKVMGSRVFPARPLNAFAPSNKLYTHCANA----- 332

Human   446 KEGDLTLYAINLHN--VTKYLRLPYPFSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTL 508
            ..|.|....:|...  .|..::.....|:.::.:|:|.   .|   .:.||||.:.|.:  :.||
  Fly   333 VSGGLAFMVVNTEEQPTTITVKSTSSLSSSEIWQYVLT---GH---DQRVQLNNVRLHL--NTTL 389

Human   509 PPLMEKPLRPGSSLGL--PAFSYSFFVIRNAKVAAC 542
            .||: ||:.|...|.|  |:.:.||:|:.:..:..|
  Fly   390 RPLI-KPIDPTKPLQLITPSMAVSFWVLPDVNLEHC 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPSE	NP_006656.2	Glyco_hydro_79n	<171..370	CDD:461010	31/180 (17%)
CG14309	NP_650718.2	None