Protein Alignment SRCAP and okr

DIOPT Version :10

• Sequence 1: NP_006653.2
• Gene: SRCAP / 10847
• HGNCID: 16974
• Length: 3230
• Species: Homo sapiens
• Sequence 2: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 493
• Identity: 131/493 - (26%)
• Similarity: 215/493 - (43%)
• Gaps: 105/493 - (21%)

Human   481 GPVEAEE-----PPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQA 540
            ||:..|.     ||....:.       ||..:|.|..:|.:.....|..::.:........:..|
  Fly    11 GPLRPESRHSFTPPLLKKNK-------RSCQQELEREQELDRRRLGALRDASNTSELPLPIRFTA 68

Human   541 DEEEEDDDFGVEYLLAR----DEEQSEADAGSGPPTPGPTTLGPKKEIT-----DIAA--AAESL 594
            :.|.|   ..:..:|||    ..:....|.|      |...||.::.|:     |..|  |....
  Fly    69 NSEYE---LAIAKVLARKFKVPMDNYVPDYG------GKRVLGVRRCISRRPLHDPMACNALVLF 124

Human   595 QPKGYT------LATTQVKTPIPL--LLRGQLREYQHIGLDWLVTMYEKK---LNG-ILADEMGL 647
            .|..||      :..|:|...:.:  ||...||.:|..|:.::....|.|   .|| |:||||||
  Fly   125 HPPAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQREGVRFMYECVEGKRGNFNGCIMADEMGL 189

Human   648 GKTIQTISLLAHLACEKGNWGPH--------LIIVPTSVMLNWEMELKRWCPSFKILTYYGAQKE 704
            |||:|.::|:..|..:    ||.        :::.|:|::.|||.|..:|... ::|.
  Fly   190 GKTLQCVTLVWTLLRQ----GPECKPTINKAIVVSPSSLVKNWEKEFTKWLHG-RLLC------- 242

Human   705 RKLKRQGWTKPNAFHV----CITSYKL----VLQDHQAFR-------RKNWRYLILDEAQNIKNF 754
              |..:|.||.|....    .:||.:|    :|..::.||       :.....:|.||...:||.
  Fly   243 --LPMEGGTKENTIRALEQFSMTSARLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNS 305

Human   755 KSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHREFKEWFSNP-LTGM---- 814
            .:..:|:|:...::||:||:|||:||.|.|.:||::|:.|.:..:...||..|.:. |.|.
  Fly   306 DNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDS 370

Human   815 --------IEGSQEYNEGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDD 871
                    ||.:||. .|||.:.       ::||....:.|.:|.|:|.||..:|:..|..||.:
  Fly   371 TEQERQRAIEKTQEL-IGLVDQC-------IIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTN 427

Human   872 FMAQTTTKETLATGHFMSVINILMQ---LRKVCNHPNL 906
            |:.....:.:||..:..:.:..|..   |:|:|:||:|
  Fly   428 FLKSDQVRRSLADCNEKASLTALADITTLKKICSHPDL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRCAP	NP_006653.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71
		HSA	127..193	CDD:462194
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..547		14/70 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	559..581		5/21 (24%)
		DEXQc_SRCAP	618..840	CDD:350761	76/261 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1017..1045
		PHA03247	<1031..1592	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1058..1125
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1138..1166
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1320..1366
		PHA03247	<1366..1834	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1406..1425
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1629..1760
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1839..1893
		SF2_C_SNF	2032..2167	CDD:350180
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2214..2233
		COG4372	2241..>2362	CDD:443500
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2271..2298
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2327..2453
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2564..2583
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2598..3081
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	3095..3230
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	12/55 (22%)
		HepA	<156..650	CDD:440319	98/332 (30%)
		DEXHc_RAD54A	156..396	CDD:350825	76/261 (29%)