Protein Alignment FAM114A2 and CG9590

DIOPT Version :10

• Sequence 1: NP_061161.2
• Gene: FAM114A2 / 10827
• HGNCID: 1333
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_650488.1
• Gene: CG9590 / 41907
• FlyBaseID: FBgn0038360
• Length: 460
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 132/507 - (26%)
• Similarity: 236/507 - (46%)
• Gaps: 96/507 - (18%)

Human    20 EDGNCEPAKNSE---------SVDQGAKPESKSEPVVSTRKRPETKPSSD----LETSKVLPIQD 71
            |||..:.|::.|         ..|:....|.:.:|......|.:.|.:::    |||.:   |..
  Fly     9 EDGGNDWAQSDEDDNWDDWGDDDDKFVHVEKEQQPQEKVSSRNDAKGTAENQEKLETPR---ISA 70

Human    72 NVSKDVPQTRWGYWGSWGKSILSSAS---ATVAT-VGQGISNVIEKAETSLGIPGPSEIS----T 128
            ..:.....:.||.||....|:|::|:   .|:.| |.||::.:|       |:|.|.|::    .
  Fly    71 PATASATSSSWGLWGGKLSSVLTTATEGLGTITTQVNQGLNQII-------GVPDPEELARINVA 128

Human   129 EVKYVAGETNAKEN-ENSSPVAGAFGVFSTISTAVQSTGKSVISGGLDALEFIGKKTMDVIAEGD 192
            |....|.:...:|| ::....:.|||:     ..|.:.|..|::.|||.||.||||||.::.:.|
  Fly   129 EKAEKAAKAPPEENVDDEKESSAAFGL-----DFVTNLGSKVLNTGLDTLEGIGKKTMTILQDND 188

Human   193 PGF---KRTKGLMNRNATLSQVLREA-KEKEEIRTS-NEVTVETDK-KTHYGLLFDEFQGLSHLE 251
            |..   ::..||...:..||.||.|| ||.:::..| .::.::..| :..:.:||:.:.||.|.|
  Fly   189 PKLMNKRKLLGLEANSPNLSAVLLEAKKEADQMEQSLQQLQLKRQKAQLRFEILFENYCGLVHFE 253

Human   252 ALEMLSQESEIKVKSILNSLSGEELETLKVELEQLKETFSLAEFCEEEEEEKKGDEDFTKDITEL 316
            |||:||:||.:|:.::|:::||.....|:..:.::||...|    |:.:.|.:||    .:..||
  Fly   254 ALEILSKESRLKLDTLLDAVSGNARAELQETINEVKELIEL----EDLDVESEGD----YEAEEL 310

Human   317 FSQLHVSSKPEKLA-RARNTAHEWIRKS--LTKPLAENEEGEKQSEAENTEQVNKNSIEDIHAFA 378
            ..:|..:.|..:|. :..:.|:.|.:..  ||                 :|:.....:|..:|.:
  Fly   311 SERLAATIKDAELGIQFDDIANHWTQSLSWLT-----------------SEEATAADLEQAYAKS 358

Human   379 IRSLAELTACSIEL--FHKTAALVL----HGRKQEVTAIERSQTLSQMTIVLCKE----LSSLSK 433
            |.:|:|  ||::|:  .||.|.|:|    |....||..:          :.||::    |..||.
  Fly   359 IHALSE--ACALEMCKLHKIAELLLVKPHHSTANEVDGV----------VNLCQQFNGHLQGLSH 411

Human   434 EFTTCLTTAGVKEMADVLNPLITAVFLEASNSASYIQDAFQLLLPVLEISLI 485
            .|...|:.   |...:.....::..|.|..::..:|:.|::|..|:|::..:
  Fly   412 RFAAVLSG---KSETEESKGRVSTFFSEMLSAVQFIEKAYKLFTPILQMGAV 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAM114A2	NP_061161.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65		13/57 (23%)
		DUF719	82..247	CDD:461625	54/179 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	342..366		3/25 (12%)
CG9590	NP_650488.1	DUF719	79..249	CDD:461625	54/181 (30%)