DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Galnt7 and Pgant9

DIOPT Version :9

Sequence 1:	NP_001161453.1	Gene:	Galnt7 / 108150	MGIID:	1349449	Length:	657	Species:	Mus musculus
Sequence 2:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster

Alignment Length:	642	Identity:	229/642 - (35%)
Similarity:	331/642 - (51%)	Gaps:	99/642 - (15%)

- Green bases have known domain annotations that are detailed below.

Mouse    43 EDRDVNNPLPNRGGNGLAPGDDRFKPVVPWPHVEGVEVDLESIRRKNKAKNEQERHAGGDSQRDV 107
            ||..:|..:...||...|..:....|.| ..|    :.||::.|.:.||..:.::....||::.:
  Fly    77 EDFGINGNVIGGGGQKQAHDEADIPPTV-GKH----KADLQAERMRKKAAEQPKKKPQEDSKKVI 136

Mouse   108 MQRQYLTFKPQTFTYRDPVLRPGVLGNFEPKEPEPHGVVGGPGEKAKPLVL----GPEYKQAVQA 168
                            ||.      .|||.          .|||..||:.|    ..|.|:||..
  Fly   137 ----------------DPP------ANFEE----------NPGELGKPVRLPKEMSDEMKKAVDD 169

Mouse   169 SIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDE-----NLLTSSVVIVFHNEGWSTLMRTVH 228
            ...:..||...||:||:.|::.|.|...||    ||     ||..:.|:|.||||.|:.|:||||
  Fly   170 GWTKNAFNQYVSDLISVHRTLPDPRDAWCK----DEARYLTNLPKTDVIICFHNEAWTVLLRTVH 230

Mouse   229 SVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKL 293
            ||:.|:|...:.:|:|:||:|:..|||.:|::|...: ..|::.|.::|||||:||.:||..||
  Fly   231 SVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAY-PKVQIIRGQKREGLIRARILGANHAK- 293

Mouse   294 GQVLIYLDAHCEVAVNWYAPLVAPISKDRATCTVPLIDYIDGNDYSIEPQQGGDEDGFARGAWDW 358
            ..||.|||:|||....|..||:..|:::..|...|:||.|  :|.::| ....|..|...|.:||
  Fly   294 SPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVI--SDETLE-YHYRDSGGVNVGGFDW 355

Mouse   359 SMLWKRIPLSHKEKAKRKHKTEPYRSPAMAGGLFAIEKDFFFELGLYDPGLQIWGGENFEISYKI 423
            ::.:...|:..:|:.:.....||..||.||||||:|:::||..||.||.|..||||||.|:|:|.
  Fly   356 NLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKT 420

Mouse   424 WQCGGKLLFVPCSRVGHIYRLEG---WQGNPPPLYVGSSPTLKNYVRVVEVWWDEYKDYFYASRP 485
            |.|||.|..||||.||||:|...   |:.       |.:...||.||:.|||.|||..|:|....
  Fly   421 WMCGGTLEIVPCSHVGHIFRKRSPYKWRS-------GVNVLKKNSVRLAEVWMDEYSQYYYHRIG 478

Mouse   486 ESKALPYGDISELKKFREDHNCKSFKWFMEEIAYDITAHYP---LPPRNVEWGEIRGLETAY--- 544
            ..|. .:||:|:.:|.|.|..||||||:::.|       ||   :|..:|..||||.|  .|
  Fly   479 NDKG-DWGDVSDRRKLRNDLKCKSFKWYLDNI-------YPELFIPGDSVAHGEIRNL--GYGGR 533

Mouse   545 -CIDS-MGKTN-----GGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGPDGSKVMITHCN- 601
             |:|: .||.:     |.:    ||||.||||.:.:::|.::.:.|.||...  |..|.:..|:
  Fly   534 TCLDAPAGKKHQKKAVGTY----PCHRQGGNQYWMLSKAGEIRRDDSCLDYA--GKDVTLFGCHG 592

Mouse   602 --LNEFKEWQYFKSLHRFTHITSGKCLDRSEVLHQVFISTCDSSKMTQKWEMNNIHS 656
              .|:|  |.|.::..:..|.||||||..||...::.:..|.:|...|:|.:.|..|
  Fly   593 GKGNQF--WTYRENTKQLHHGTSGKCLAISESKDKLLMEECSASLSRQQWTLENYDS 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galnt7	NP_001161453.1	pp-GalNAc-T	210..518	CDD:133004	133/310 (43%)
		BcsA	210..>438	CDD:224136	101/227 (44%)
		Ricin_B_lectin	534..649	CDD:279046	42/127 (33%)
		RICIN	535..651	CDD:238092	43/128 (34%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	122/282 (43%)
		pp-GalNAc-T	213..510	CDD:133004	134/316 (42%)
		Ricin_B_lectin	521..640	CDD:279046	42/128 (33%)
		RICIN	523..642	CDD:238092	43/128 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750