DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc22a7 and CG33233

DIOPT Version :9

Sequence 1:	NP_659105.2	Gene:	Slc22a7 / 108114	MGIID:	1859559	Length:	540	Species:	Mus musculus
Sequence 2:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster

Alignment Length:	252	Identity:	53/252 - (21%)
Similarity:	106/252 - (42%)	Gaps:	45/252 - (17%)

- Green bases have known domain annotations that are detailed below.

Mouse   152 GVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLP 216
            |::...:..|:|:||:||:.::.:|.|..|:..::||...:.......|::.|:.|:....:.:.
  Fly    68 GMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVG 132

Mouse   217 LELEWLDVEHRTVAGVISTTFWTGGVLLLTLV---------------GYLIRSWRWLLLAATLPC 266
            ...|:..::.|.:...|.:......::...||               .|.:|.||:|::...:|.
  Fly   133 FLGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMFFMIPG 197

Mouse   267 VPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGR-------PISEDSLS---QEALNKVI 321
            ...::.|..|||:..:|::..|.::|...|....::|.:       .:||:..|   ||...|.:
  Fly   198 WLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEEKSSTNDQEGFWKTV 262

Mouse   322 TME--RVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGL--------TLDASG 368
            ..|  .:..:|.....|          .|:.:.||:.|:..||        .:|.||
  Fly   263 WYEYKLLFSKPHVFKFF----------ICLFLIFGIFFTSIGLGIWFPVIRNMDNSG 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a7	NP_659105.2	2A0119	11..521	CDD:273328	53/252 (21%)
Slc22a7	NP_659105.2	MFS	146..511	CDD:119392	53/252 (21%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	53/252 (21%)
		MFS	23..>208	CDD:119392	27/139 (19%)
		MFS	354..>482	CDD:304372
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840