Protein Alignment WASF3 and gukh

DIOPT Version :10

• Sequence 1: NP_006637.2
• Gene: WASF3 / 10810
• HGNCID: 12734
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_732393.1
• Gene: gukh / 53563
• FlyBaseID: FBgn0026239
• Length: 1788
• Species: Drosophila melanogaster
• Alignment Length: 326
• Identity: 75/326 - (23%)
• Similarity: 123/326 - (37%)
• Gaps: 69/326 - (21%)

Human    25 ELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVKVTQLDS---T 86
            |.:.::|.||:..:|||:||...|.|||.:|..:......||..:|.:|..:..:|...|.   |
  Fly   138 EFDSISNITLSNALRQLASLVLIASDIFDDLQRDLQAVGERAGRVQRKIAAVERRVCAYDPKTVT 202

Human    87 VEEVSLQDINMKK-AFKSSTVQDQQVVSKNSIPNPVADIYNQSDKPPPL---------------N 135
            |.|..|.....:| .|::.....|::.:..:.|..|..:|.::.|..|:               .
  Fly   203 VPESDLLTFAQRKHHFETDKSFQQELFTGETRPLSVRQLYTEAGKELPVATGATATALASLAHSQ 267

Human   136 ILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQ-----DTED-----KRKEKRRQKEQKRIDGTTR 190
            .|.|.|....:|....:|         .::||     ||||     .......:|.:.|||.
  Fly   268 SLIPSRSISFNGEVLSSD---------HEVLQLNGSTDTEDHLLCVSDFGNANRKLRTRIDA--- 320

Human   191 EVK-KVRKARNRRQEWNMMAY--DKELRP------DNRLSQSVYHGASS--EGSLSPDTRSHASD 244
            |:: ::..|....::|.....  |..:.|      |..:|.|:..|.:.  ..:|||...|  :|
  Fly   321 EIEIRLPAAIEDLRKWTSSEALGDVTVTPDCMHHVDTSVSTSLAIGENGILTPALSPSVLS--AD 383

Human   245 VTDYSYPA-------TPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQ 302
            ..|..|..       :..|:.|.|.:.|:....|||        ..|....|....:.:||..|.
  Fly   384 AVDALYAQNLSQAADSSRHNHHTQALIPNDINKDVP--------LNHRLPSPEEQTKQIALKYPA 440

Human   303 Q 303
            :
  Fly   441 E 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WASF3	NP_006637.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..210		10/46 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	223..443		21/90 (23%)
		WH2_WAVE-3	437..502	CDD:409216
		actin-binding sequence	454..457	CDD:409216
gukh	NP_732393.1	None