Protein Alignment HSPH1 and CG7182

DIOPT Version :9

• Sequence 1: NP_001273433.1
• Gene: HSPH1 / 10808
• HGNCID: 16969
• Length: 860
• Species: Homo sapiens
• Sequence 2: NP_001286979.1
• Gene: CG7182 / 38944
• FlyBaseID: FBgn0035878
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 118/529 - (22%)
• Similarity: 208/529 - (39%)
• Gaps: 108/529 - (20%)

Human    44 GSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDL--VPLKNGGVGIKVM 106
            |:.....|:.||.:........|:     |......|..:..:|.||..|  :|..
  Fly    45 GASEIECGLTAKQKMANRPRQAVA-----HSFQLLQPKEELTEEKLSSALREIPCD--------- 95

Human   107 YMGEEHLFSVE----------------------QITAMLLTKLKETAE----NSLKKPVTDCVIS 145
            :..||.:|.:|                      |:|..||....|.|.    :..:.|:  .|:|
  Fly    96 FDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQVTVELLRAELELAHQYHTDGEQAPI--AVLS 158

Human   146 VPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAF 210
            :||::..:..:.:.||||..|.:..:::.:.||..|.|.|.::.    .|:.|.|:.:..|....
  Fly   159 IPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAVLGYSIGEEQ----TEQRRHVLTIKCGGLYS 219

Human   211 QVSACAFNKGKLKVLGTAFDPF-LGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEK 274
            .::..:...|....|.| |.|| :||:.|.|.||:..|.||:.|||||.....|::.::......
  Fly   220 DIAFYSVQNGLFVQLAT-FGPFPIGGRQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAAN 283

Human   275 LKKLMSSNSTDLP---LNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQT---HLK 333
            .|.::    |.:|   |.|:..|:..|.:.:|:|::||.|...::..:...|...:||.   |..
  Fly   284 CKHIL----TTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPG 344

Human   334 VEDVSAVEIVGGATRIPAVKERI-AKFFGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVT 397
            :..:..:.::|...:||.::..: |:|....:..:.:|||.||.|||.|...|....:.:.....
  Fly   345 LSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVVAIGCARQAVCLIDPLEQQLHKEE 409

Human   398 DAVPFPISL-IWNHDSEDTEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKI 461
            |.|.....| ||:.:.|....:  |..|....| :|:                   .:..|:::.
  Fly   410 DCVVAEDDLFIWHGNDESNAKL--VLGRGSVLP-AKI-------------------RISLPQSEE 452

Human   462 GRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEEN--EMSSEADMECLNQRPP 524
            |:        ..|..|:....|:|.....|.    |.:.:....|:.  ::..|.|::
  Fly   453 GK--------GDDVSKAAASFKLRTGESEIL----ARLPDSTIPEDGLYQLEVEVDVD------- 498

Human   525 ENPDTDKNV 533
               |.|.||
  Fly   499 ---DKDGNV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPH1	NP_001273433.1	NBD_sugar-kinase_HSP70_actin	39..386	CDD:327376	92/377 (24%)
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	91/373 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900