| Sequence 1: | NP_065433.2 | Gene: | ADCY2 / 108 | HGNCID: | 233 | Length: | 1091 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001097148.1 | Gene: | Gyc32E / 34553 | FlyBaseID: | FBgn0010197 | Length: | 1191 | Species: | Drosophila melanogaster |
| Alignment Length: | 352 | Identity: | 103/352 - (29%) |
|---|---|---|---|
| Similarity: | 166/352 - (47%) | Gaps: | 79/352 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Human 773 YNTILLHTHAHVLGDY-----SQVLFERPGIWKDLKTM--------GSVSLSIFFITLLVLGRQN 824
Human 825 EYYC---------RLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYH 880
Human 881 QSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNE-------IIADFDDLLSKPKFSGVEKI 938
Human 939 KTIGSTYMAATGLSAVPSQEHSQEPERQYMHIGTMVEFAFAL---VGKLDAINKHSFNDFKLRVG 1000
Human 1001 INHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLG-YTCTCRGIIN 1064
Human 1065 VKGKGDLKTYFVNTEMSRSLSQSNVAS 1091 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ADCY2 | NP_065433.2 | AcyC | 59..470 | CDD:441717 | |
| Guanylate_cyc | 281..465 | CDD:425528 | |||
| Adcy_cons_dom | 495..600 | CDD:461877 | |||
| Guanylate_cyc | 878..1077 | CDD:425528 | 74/209 (35%) | ||
| Interaction with GNAS. /evidence=ECO:0000250|UniProtKB:P26769 | 905..922 | 5/23 (22%) | |||
| Interaction with GNAS. /evidence=ECO:0000250|UniProtKB:P26769 | 990..993 | 0/2 (0%) | |||
| Gyc32E | NP_001097148.1 | PBP1_SAP_GC-like | 44..448 | CDD:380593 | |
| PK_GC-A_B | 550..832 | CDD:270944 | 10/46 (22%) | ||
| CYCc | 865..1057 | CDD:214485 | 75/232 (32%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||