Sequence 1: | NP_065433.2 | Gene: | ADCY2 / 108 | HGNCID: | 233 | Length: | 1091 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001259575.1 | Gene: | Ac13E / 32485 | FlyBaseID: | FBgn0022710 | Length: | 1703 | Species: | Drosophila melanogaster |
Alignment Length: | 1606 | Identity: | 354/1606 - (22%) |
---|---|---|---|
Similarity: | 571/1606 - (35%) | Gaps: | 637/1606 - (39%) |
- Green bases have known domain annotations that are detailed below.
Human 29 SRDWLYESY--YCMSQQHPLIVF----------LLLIVMGSCLALLAVFFALGLEVEDHVAFLIT 81
Human 82 VPTALAIFFAIFIL-VCIE--SVFKKLLRLFSLVIWICLVAMGYLFMCF-GGTVSPWDQVSFFLF 142
Human 143 IIFVVYTMLPFNM----RDAIIASV-LTSSSHTIVLSVCLSATPGGKEH---------------- 186
Human 187 -----LVWQILANVIIFICGNLAGAYHKHLMELA-LQQTYQDTCNCIKSRIKLEFEKRQQERLLL 245
Human 246 SLLPAHIAMEMKAEIIQRLQGPK---AGQM---------ENTNNFHNLYVKRH----TNVSILYA 294
Human 295 DIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCV 359
Human 360 KMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGR 424
Human 425 VHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERR------------------ 471
Human 472 ------------------------------------------SPQHLFRPRHTLDGAKMR----- 489
Human 490 ------------------------------------------------------------ASVRM 494
Human 495 TRYLESW------------------GAAKPFAH---------------LHHRDSMTTE------- 519
Human 520 --------------------NGKISTTDVPM---------------------------------- 530
Human 531 -GQHNF------------QNRT------------------------------------------- 539
Human 540 ----------------------------------------------------------------- 539
Human 540 -------LRTKSQKKRFEEE---LNE--------------------------------------- 555
Human 556 ---------------------------RMIQAI-DGINAQKQWLKSEDIQRISLLFYNKVLEKEY 592
Human 593 RA----------------TALPAFKYYVT--CACLIFFCIFIVQILVLPKTSVLGISFGAAFLLL 639
Human 640 AFILFVCFAG----QLLQCSKKASPLLMWLLKSSGIIANR------------------------- 675
Human 676 ----------------PWPRISLTIITTAIILMMAVFNMFFLSDSEETIPPTANTTNTSFSASNN 724
Human 725 QVAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVA---LVGYNTILLHTHAHVLG 786
Human 787 DYSQVLFERPGIWKDLKTMGSVSLSIFFITLLV------LGRQNEYYCRLDFLWKNKFKKEREEI 845
Human 846 ETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGL 910
Human 911 ECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHSQEPERQYMHIGTMVE 975
Human 976 FAFALVGKLDAINKH--SFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLD 1038
Human 1039 KIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSL 1084 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ADCY2 | NP_065433.2 | AC_N | <33..260 | CDD:292831 | 54/269 (20%) |
CYCc | 236..439 | CDD:214485 | 88/218 (40%) | ||
Guanylate_cyc | 281..465 | CDD:278633 | 87/187 (47%) | ||
DUF1053 | 495..599 | CDD:283888 | 29/411 (7%) | ||
CYCc | 848..1056 | CDD:214485 | 102/209 (49%) | ||
Guanylate_cyc | 878..1077 | CDD:278633 | 95/200 (48%) | ||
Interaction with GNAS. /evidence=ECO:0000250|UniProtKB:P26769 | 905..922 | 8/16 (50%) | |||
Interaction with GNAS. /evidence=ECO:0000250|UniProtKB:P26769 | 990..993 | 0/4 (0%) | |||
Ac13E | NP_001259575.1 | CYCc | 302..518 | CDD:214485 | 89/220 (40%) |
Guanylate_cyc | 361..535 | CDD:278633 | 85/184 (46%) | ||
CYCc | 1362..1556 | CDD:214485 | 102/209 (49%) | ||
Guanylate_cyc | 1388..1575 | CDD:278633 | 95/197 (48%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG2114 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |