DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gcm2 and gcm2

DIOPT Version :10

Sequence 1:NP_032130.2 Gene:Gcm2 / 107889 MGIID:1861438 Length:504 Species:Mus musculus
Sequence 2:NP_609302.1 Gene:gcm2 / 34280 FlyBaseID:FBgn0019809 Length:606 Species:Drosophila melanogaster


Alignment Length:488 Identity:161/488 - (32%)
Similarity:213/488 - (43%) Gaps:147/488 - (30%)


- Green bases have known domain annotations that are detailed below.


Mouse     1 MPADSTQDEDAVLSYGMKLTWDINDPQMPQEP-THFDHFREWPDGYVRFIYSSQEKKAQRHLSGW 64
            ||:.||...        |..|||||..:|..| ..||.|.||.||:||.|||...::|::|:|||
  Fly    55 MPSSSTGKG--------KREWDINDAIVPHVPDQEFDEFNEWSDGHVRHIYSLHNEEAKKHISGW 111

Mouse    65 AMRNTNNHNGHILKKSCLGVVVCARACALKDGSHLQLRPAICDKARLKQQKKACPN--CH-SPLE 126
            |||||||||.:|||||||||:||::.|.|.:||.:.||||||||||.||:.|||||  |. ..||
  Fly   112 AMRNTNNHNVNILKKSCLGVLVCSQHCTLPNGSKINLRPAICDKARRKQEGKACPNKSCRGGRLE 176

Mouse   127 LVPCRGHSGYPVTNFWRLDGNAIFFQAKGVHDHPRPESKSETEGRRS---------------ALK 176
            :.|||||.|||||:|||..||||||||||||||.||:.|:.:..:|:               |.|
  Fly   177 IKPCRGHCGYPVTHFWRHSGNAIFFQAKGVHDHLRPDPKNSSVSKRAFGRVPLAGKSANGSVAKK 241

Mouse   177 RQMASFYQPQKRRS------------GEPEARSTQDI---------RGHLNSTAALEPTELFDMT 220
            ..:|...:..|::.            ..|.|.:..||         .|:.:.|.:.    |.|.|
  Fly   242 SVIAGLVKQAKQQHSLISKVLKRPAVSNPLAHTALDIYQYNACGKCAGYSHCTCSY----LDDST 302

Mouse   221 -------------ADTSFPIPGQPS--PSFPNSDVYRVTCDLPTFQGDIILPFQKYPNPSIYFPG 270
                         ...|:|:.|..|  |....::|:.|.....|:         .||   ||...
  Fly   303 TARSHQLSQSSNYGTNSWPLSGSESSAPCETAANVFTVNHQHITY---------NYP---IYHAT 355

Mouse   271 PPWGYELASSGVTGSSPYSTLYKDSSEVPDDPDWIPLNSLQY--NVSSYGSYERTLDFTARYHSW 333
            |     .|::.....||                     ||.|  ::|...:|:::....: :...
  Fly   356 P-----AAATAAPSKSP---------------------SLPYACSISELAAYQQSSSGNS-FAMG 393

Mouse   334 KPTHGKPSLEEKVDCEQCQAV----------PTLPYYNL-------------ELPCRYLPVPAAG 375
            .|.||.         .|||||          |...:.|.             |:.|:..|.|...
  Fly   394 VPVHGH---------TQCQAVAYDSSPQLATPEPEFINYSQIKHLGGGGGQEEISCKAEPGPTIK 449

Mouse   376 SQALQTVITTTVA---YQAYQHPALKHGDSMQE 405
            ..|  ||.|....   |..|..|..::  .||:
  Fly   450 YNA--TVETQPYVEDNYDYYYSPKAEY--EMQQ 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gcm2NP_032130.2 GCM 35..172 CDD:397602 91/139 (65%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 155..203 17/83 (20%)
C-terminal conserved inhibitory domain (CCID). /evidence=ECO:0000250|UniProtKB:O75603 379..393 4/16 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 438..472
gcm2NP_609302.1 GCM 82..222 CDD:397602 91/139 (65%)
Blue background indicates that the domain is not in the aligned region.

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