DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gcm2 and gcm

DIOPT Version :10

Sequence 1:NP_032130.2 Gene:Gcm2 / 107889 MGIID:1861438 Length:504 Species:Mus musculus
Sequence 2:NP_477108.1 Gene:gcm / 34277 FlyBaseID:FBgn0014179 Length:504 Species:Drosophila melanogaster


Alignment Length:510 Identity:160/510 - (31%)
Similarity:216/510 - (42%) Gaps:142/510 - (27%)


- Green bases have known domain annotations that are detailed below.


Mouse    19 LTWDINDPQMPQEPTHFDHFREWPDGYVRFIYSSQEKKAQRHLSGWAMRNTNNHNGHILKKSCLG 83
            :.|||||.:|| ....||.|.:|.:|:.|.|||.|..:|::|.||||||||||||.:||||||||
  Fly    32 IDWDINDSKMP-SVGEFDDFNDWSNGHCRLIYSVQSDEARKHASGWAMRNTNNHNVNILKKSCLG 95

Mouse    84 VVVCARACALKDGSHLQLRPAICDKARLKQQKKACP--NCHSPLELVPCRGHSGYPVTNFWRLDG 146
            |::|:..|.|.:|:.:.||||||||||.|||.|.||  ||:..||:..||||.|||||:|||.||
  Fly    96 VLLCSAKCKLPNGASVHLRPAICDKARRKQQGKQCPNRNCNGRLEIQACRGHCGYPVTHFWRRDG 160

Mouse   147 NAIFFQAKGVHDHPRPESKSETEGRR------------------SALKRQMASFYQPQKRRSGEP 193
            |.|:|||||.|||||||:|..||.||                  |||..:::|. :|.||::   
  Fly   161 NGIYFQAKGTHDHPRPEAKGSTEARRLLAGGRRVRSLAVMLARESALSDKLSSL-RPTKRQA--- 221

Mouse   194 EARSTQDI----RGHLNSTAALEPTELFDMTADTSFPIPGQP--SPSFPNSDVYRVTCDLPTFQG 252
               .||.|    |..:.::..||..:...:...|..| ...|  |.:|..|....|    |..||
  Fly   222 ---KTQSIQESKRRRMGASDVLETKQELVVPPTTYLP-TSTPTHSTNFNQSQGSYV----PAGQG 278

Mouse   253 DIILPFQK---YPNPSIYFPGPPWGYELASSGVTGSSPYSTLYKDSS------------------ 296
            .:|..:.:   |......:....:.|::..|.::..|...:.|:::.                  
  Fly   279 SVISQWNREIHYETEDPCYANGMYSYDMLHSPLSAHSSTGSYYQENKPQQLQHSQYQQQLSPQQH 343

Mouse   297 -EVPDDPDWIPLNSLQYNVSSYGSYERTLDFTARYHSWKPTHGKPSLEEKVDCEQCQAVPTLPYY 360
             .|..||.....:|||..:.||...:.|...|:........:|                    ||
  Fly   344 VPVSYDPSQPISSSLQCGMPSYEICDDTSSLTSSSGYCSEDYG--------------------YY 388

Mouse   361 NLELPCRYLP----------------------------------VPAAGSQALQTVITTTVAYQA 391
            |     .|||                                  :...|:..:..:.....|||.
  Fly   389 N-----GYLPNSLDVSNGSQSQNLSQDASFYTTSSEIFSVFESTLNGGGTSGVDLIYDEATAYQQ 448

Mouse   392 YQH----PALKH-----GDSMQEVSSLAS-------------CTYASENLPMPIY 424
            :|.    |.|.:     .|.||......|             .||...|...|||
  Fly   449 HQQQGTFPHLTNYQQEPQDQMQSADYYYSNTGVDNSWNIQMDATYHPVNSTDPIY 503

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gcm2NP_032130.2 GCM 35..172 CDD:397602 88/138 (64%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 155..203 23/69 (33%)
C-terminal conserved inhibitory domain (CCID). /evidence=ECO:0000250|UniProtKB:O75603 379..393 3/13 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 438..472
gcmNP_477108.1 GCM 47..186 CDD:397602 88/138 (64%)
Blue background indicates that the domain is not in the aligned region.

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