DRSC/TRiP Functional Genomics Resources

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Protein Alignment GRAP and Csk

DIOPT Version :10

Sequence 1:NP_006604.1 Gene:GRAP / 10750 HGNCID:4562 Length:217 Species:Homo sapiens
Sequence 2:NP_731611.2 Gene:Csk / 41398 FlyBaseID:FBgn0262081 Length:1052 Species:Drosophila melanogaster


Alignment Length:89 Identity:30/89 - (33%)
Similarity:49/89 - (55%) Gaps:13/89 - (14%)


- Green bases have known domain annotations that are detailed below.


Human    53 IRVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGK 117
            :::...||:.|.|:|..||.:|..|.. |.||:|||.:.||::::.|.:..:|:|::|      |
  Fly   677 VKLNAMPWFHGSITRDEAEHLLQPRED-GLFLVRESTNFPGDYTLCVCFQSKVEHYRV------K 734

Human   118 YFL------WEEKFNSLNELVDFY 135
            |..      .||.|.:|.:||..|
  Fly   735 YLENKLTIDDEEYFENLGQLVAHY 758

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GRAPNP_006604.1 SH3_GRAP_N 2..55 CDD:212881 0/1 (0%)
SH2_Grb2_like 56..150 CDD:199828 30/86 (35%)
SH3_GRAP_C 162..214 CDD:212884
CskNP_731611.2 SH2_csk_like 680..777 CDD:198190 30/86 (35%)
PTKc_Csk_like 793..1047 CDD:270635
Blue background indicates that the domain is not in the aligned region.

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