Protein Alignment GRAP and Src42A

DIOPT Version :10

• Sequence 1: NP_006604.1
• Gene: GRAP / 10750
• HGNCID: 4562
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 53/177 - (29%)
• Similarity: 81/177 - (45%)
• Gaps: 26/177 - (14%)

Human    38 KAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAE-EILMKRNHLGAFLIRESESSPGEFSVSVNY 101
            |.:.|.:..|....::..|  .||..:|.|..|| ::|:..|..||||||:|||...::|:||..
  Fly  1190 KGKSRRLSEFTRGEFLNEK--SWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRD 1252

Human   102 GDQVQHFKVLREASGKYFLWEE-KFNSLNELVDFYRTTTIAKKRQIFLRDEEPL---LKSPGACF 162
            ||.|:|:::.:...|.:|:... .|.:|.|||:.|.            :|.:.|   |..|  |.
  Fly  1253 GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYS------------KDSDGLCVNLCKP--CV 1303

Human   163 AQAQFD--FSAQDP--SQLSFRRGDIIEVLERPDPHWWRGRSCGRVG 205
            ....|.  |..:.|  ..||.|..|..|: :|....:.|....|:.|
  Fly  1304 QTNSFSGVFEIEKPVTEGLSHRTRDQWEI-DRTSLKFVRKLGSGQFG 1349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GRAP	NP_006604.1	SH3_GRAP_N	2..55	CDD:212881	3/16 (19%)
		SH2_Grb2_like	56..150	CDD:199828	33/95 (35%)
		SH3_GRAP_C	162..214	CDD:212884	12/48 (25%)
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233	35/102 (34%)
		PTKc_Frk_like	1328..1596	CDD:270653	6/23 (26%)