Protein Alignment CFL2 and cfl2

DIOPT Version :10

• Sequence 1: NP_068733.1
• Gene: CFL2 / 1073
• HGNCID: 1875
• Length: 166
• Species: Homo sapiens
• Sequence 2: NP_001011156.1
• Gene: cfl2 / 496574
• XenbaseID: XB-GENE-1002956
• Length: 167
• Species: Xenopus tropicalis
• Alignment Length: 166
• Identity: 146/166 - (87%)
• Similarity: 155/166 - (93%)
• Gaps: 0/166 - (0%)

Human     1 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVE 65
            ||||||||||||||||:||||||||.|||||||||||||||.||::|||||.|||||||||:.|.
 Frog     1 MASGVTVNDEVIKVFNEMKVRKSSTPEEIKKRKKAVLFCLSPDKKEIIVEETKQILVGDIGEAVP 65

Human    66 DPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTG 130
            |||.:||.||||:||||.|||||||||||||||||||||||::||||||||||||||||||||||
 Frog    66 DPYRTFVNLLPLDDCRYGLYDATYETKESKKEDLVFIFWAPDNAPLKSKMIYASSKDAIKKKFTG 130

Human   131 IKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL 166
            ||||||||||||||||.||.:||||||||||||.||
 Frog   131 IKHEWQVNGLDDIKDRCTLADKLGGNVVVSLEGVPL 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CFL2	NP_068733.1	Interaction with CSRP3. /evidence=ECO:0000269|PubMed:19752190	2..55		46/52 (88%)
		ADF_cofilin_like	3..153	CDD:200442	130/149 (87%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		3/3 (100%)
		Interaction with CSRP3. /evidence=ECO:0000269|PubMed:19752190	55..105		41/49 (84%)
cfl2	NP_001011156.1	ADF_cofilin_like	3..153	CDD:200442	130/149 (87%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		3/3 (100%)