Protein Alignment CFL2 and cfl2

DIOPT Version :10

• Sequence 1: NP_068733.1
• Gene: CFL2 / 1073
• HGNCID: 1875
• Length: 166
• Species: Homo sapiens
• Sequence 2: NP_991263.1
• Gene: cfl2 / 403001
• ZFINID: ZDB-GENE-040426-1815
• Length: 166
• Species: Danio rerio
• Alignment Length: 166
• Identity: 148/166 - (89%)
• Similarity: 159/166 - (95%)
• Gaps: 0/166 - (0%)

Human     1 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVE 65
            |||||||:||||||||||||||||:.:|:|||||||||||||||::|||||.:|||||||||:|:
Zfish     1 MASGVTVSDEVIKVFNDMKVRKSSSSDEVKKRKKAVLFCLSDDKKKIIVEEGRQILVGDIGDSVD 65

Human    66 DPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTG 130
            |||..||||||||||||.||||||||||||||||||||||||.||||||||||||||||||||||
Zfish    66 DPYACFVKLLPLNDCRYGLYDATYETKESKKEDLVFIFWAPEGAPLKSKMIYASSKDAIKKKFTG 130

Human   131 IKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL 166
            |||||||||||||:|||||.|||||||||||||:||
Zfish   131 IKHEWQVNGLDDIQDRSTLAEKLGGNVVVSLEGRPL 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CFL2	NP_068733.1	Interaction with CSRP3. /evidence=ECO:0000269|PubMed:19752190	2..55		43/52 (83%)
		ADF_cofilin_like	3..153	CDD:200442	132/149 (89%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		3/3 (100%)
		Interaction with CSRP3. /evidence=ECO:0000269|PubMed:19752190	55..105		44/49 (90%)
cfl2	NP_991263.1	ADF_cofilin_like	3..153	CDD:200442	132/149 (89%)