Protein Alignment CFL2 and CG6873

DIOPT Version :10

• Sequence 1: NP_068733.1
• Gene: CFL2 / 1073
• HGNCID: 1875
• Length: 166
• Species: Homo sapiens
• Sequence 2: NP_573321.1
• Gene: CG6873 / 32861
• FlyBaseID: FBgn0030951
• Length: 148
• Species: Drosophila melanogaster
• Alignment Length: 138
• Identity: 40/138 - (28%)
• Similarity: 71/138 - (51%)
• Gaps: 22/138 - (15%)

Human     1 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVE 65
            ||||:.::.|...||.  ::||      :|:.:.||.  :..|:|:|.||      |..:.:...
  Fly     1 MASGINLSRECQHVFE--QIRK------LKQHRYAVF--VIQDEREIKVE------VLGVREANY 49

Human    66 DPYTSFVKLLPLNDCRYALYDATYE------TKESKKEDLVFIFWAPESAPLKSKMIYASSKDAI 124
            |.:.:.::....|.||:|:||..|:      .....||.|:.:.|.|..|.:|.||:|:|:...:
  Fly    50 DDFLADLQRAGSNQCRFAVYDYEYQHQCQGTLSTCLKEKLILMLWCPTLARIKDKMLYSSTFAVL 114

Human   125 KKKFTGIK 132
            |::|.|::
  Fly   115 KREFPGVQ 122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CFL2	NP_068733.1	Interaction with CSRP3. /evidence=ECO:0000269|PubMed:19752190	2..55		16/52 (31%)
		ADF_cofilin_like	3..153	CDD:200442	38/136 (28%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		1/3 (33%)
		Interaction with CSRP3. /evidence=ECO:0000269|PubMed:19752190	55..105		12/55 (22%)
CG6873	NP_573321.1	ADF_cofilin_like	3..142	CDD:200442	38/136 (28%)