Protein Alignment BOLA2-SMG1P6 and MEC1

DIOPT Version :9

• Sequence 1: NP_001307551.1
• Gene: BOLA2-SMG1P6 / 107282092
• HGNCID: 53563
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_009694.3
• Gene: MEC1 / 852433
• SGDID: S000000340
• Length: 2368
• Species: Saccharomyces cerevisiae
• Alignment Length: 258
• Identity: 59/258 - (22%)
• Similarity: 99/258 - (38%)
• Gaps: 74/258 - (28%)

Human    73 YLREK-LQRDLEAEHVLPSPGGVGQVRGET----AASETQVLYRVM---RCVTAANQVFFSEAVL 129
            |||.| .:|.::.     :|..|||....|    |..:|...:|.:   .|...|
Yeast  1068 YLRRKQTERSIDF-----TPKKVGQTSDITLVLGALLDTSHKFRNLDKDLCEKCA---------- 1117

Human   130 TAANECVGVLLGSLDPSMTIHCDMVITYGLDQL----ENCQTCGTDYIISVLNLLTLIVEQINTK 190
                :|:. ::|.||  :|.|.....||..:::    ::.||  ..::|.|:|.: |:.....::
Yeast  1118 ----KCIS-MIGVLD--VTKHEFKRTTYSENEVYDLNDSVQT--IKFLIWVINDI-LVPAFWQSE 1172

Human   191 LPSSFVEKLFIPSSKLLFLRY-----------HKEKEVVAVAHAVY--QAMLSLKNIPVLETAYK 242
            .||   ::||:.......|:|           |||         :|  :|.|..|...|.:|
Yeast  1173 NPS---KQLFVALVIQESLKYCGLSSESWDMNHKE---------LYPNEAKLWEKFNSVSKT--- 1222

Human   243 LILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVKFDLSALTTIGNAKNSSL 305
                    .:..||.||.|.::..|.....:.::.|......:|.:|.|..|.| |..:|..|
Yeast  1223 --------TIYPLLSSLYLAQSWKEYVPLKYPSNNFKEGYKIWVKRFTLDLLKT-GTTENHPL 1276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BOLA2-SMG1P6	NP_001307551.1	None
MEC1	NP_009694.3	TEL1	194..2368	CDD:227365	59/258 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900