Protein Alignment CCT6B and CCT3

DIOPT Version :10

• Sequence 1: NP_006575.2
• Gene: CCT6B / 10693
• HGNCID: 1621
• Length: 530
• Species: Homo sapiens
• Sequence 2: NP_650572.2
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 153/547 - (27%)
• Similarity: 278/547 - (50%)
• Gaps: 70/547 - (12%)

Human     8 NSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHP 72
            |:|.|  ..|.....||.|.:.:.||:||.|||:..:|||:...|.|.:|.|||.:|.|:.:|||
  Fly    14 NTKRE--SGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREITVQHP 76

Human    73 TASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALE----- 132
            .|..:.::|..||:..||||||.:::.||:|..|:.::.:.:||.:|...:.    :|||
  Fly    77 AAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYR----EALEDIVGH 137

Human   133 VLEEVKVTKEMKRKI-LLDVARTSLQTKVHAELADVLTEVVVDSVLAV----------------- 179
            :..::.:..::|.|. :.||.:..:.||...:.:|:..::.:|:|..|
  Fly   138 LQSQLSIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDIKRYAK 202

Human   180 --RRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKT 242
              :.||..|:               ::.:::|::::....||.|::.:|:..|::.:.||||:|.
  Fly   203 VEKIPGGAIE---------------ESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKG 252

Human   243 EVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQ--SNKGFVVINQKGIDPFSLDSL 305
            |..:.......::..::::.|.:|::           ::||.  :.|..:|..:||:...:...|
  Fly   253 ESQTNVEIIGEQDFTRMLQIEEEFVQ-----------RICADIIAVKPDLVFTEKGVSDLAQHYL 306

Human   306 AKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLG-HAGLVYEYTLGEEKFTFIEECVNP 369
            .|.||.|:||.::.:..|::.|||...||..|:||...:| .|||.....:|:|.|||:.||..|
  Fly   307 LKAGITAIRRLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEP 371

Human   370 CSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRAR 434
            .:.|:|::|.:|..|.:.:..::|.|...:|.:.:..:|.|.||:|:|.::.|.  :..:||
  Fly   372 KACTILLRGASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLT--RKQVKG--- 431

Human   435 LGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV----ESKQLVGVDLNTGEPMVAADAGVW 495
             ...|.|.||.|||:.||||.|.:....|..::|:|.    :.....|:|..:||.:......:|
  Fly   432 -PYTAVAHALEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIW 495

Human   496 DNYCVKKQLLHSCTVIATNILLVDEIM 522
            :...||.|...:....|..:|.:|:|:
  Fly   496 EPLAVKLQTYKTAVETAILLLRIDDIV 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6B	NP_006575.2	chap_CCT_zeta	3..530	CDD:274088	153/547 (28%)
CCT3	NP_650572.2	chap_CCT_gamma	7..528	CDD:274085	153/547 (28%)