Protein Alignment GNA13 and Galphaf

DIOPT Version :10

• Sequence 1: NP_006563.2
• Gene: GNA13 / 10672
• HGNCID: 4381
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_524118.1
• Gene: Galphaf / 39861
• FlyBaseID: FBgn0010223
• Length: 399
• Species: Drosophila melanogaster
• Alignment Length: 360
• Identity: 136/360 - (37%)
• Similarity: 200/360 - (55%)
• Gaps: 41/360 - (11%)

Human    49 VKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDN 113
            |||||||..||||:|.:|||||:|...|....|.|..|.||.|:.:.:..||.....|.|.:|..
  Fly    48 VKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSC 112

Human   114 SNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFL 178
            ::::..|.::|....||   :.|.|     :|...:..||.|.||:..|||..||.|.:|.||||
  Fly   113 TSERSADYILSLPGSAP---EYMNE-----EYCDHVTTLWNDVGIRACYDRSNEFPLLDSAKYFL 169

Human   179 DNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVP---------FKMVDVGGQRSERKRWF 234
            ||..::.:.:||||.:|||.:|:.|.||.:..|.:. :|         |:|.||||||.:|.:|.
  Fly   170 DNFVRISDAEYIPSTEDILHSRKITTGISQITFRVP-IPKSMGGGEQQFQMYDVGGQRDQRNKWI 233

Human   235 ECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEK 299
            :.|:.:.::|||:|.|||||.|.||...|||.|:|.:|..:..||..::..:|:||||.|::|.|
  Fly   234 QVFEGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLASAGLIVFLNKYDIMERK 298

Human   300 VQI-VSIKDYFLEFEG------DPHCLRD-------VQKFLV----ECFRNKRRDQ-----QQKP 341
            ::. ..|.|||.|:|.      ..:|..:       :::.||    |.|:...|:|     .::.
  Fly   299 IRAGKHIVDYFPEYEDFCKRPQQDNCFGESDWTKMFIKQKLVDITQEPFKRHSRNQVDLGTSERE 363

Human   342 LYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376
            .|:|||.|.:|..||.||.||:..||.:|:..:.|
  Fly   364 CYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNA13	NP_006563.2	G_alpha	29..375	CDD:214595	135/357 (38%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	50..63		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	195..203		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	218..227		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	287..294		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	347..352		2/4 (50%)
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	135/357 (38%)