Protein Alignment GNA13 and CG17760

DIOPT Version :10

• Sequence 1: NP_006563.2
• Gene: GNA13 / 10672
• HGNCID: 4381
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_001036539.1
• Gene: CG17760 / 36385
• FlyBaseID: FBgn0033756
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 359
• Identity: 149/359 - (41%)
• Similarity: 220/359 - (61%)
• Gaps: 9/359 - (2%)

Human    18 CLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRARE 82
            |.|:....|::|.|:||||.|..||...:|.:|:|:||.|||||:||:||||||||:.|..:.|:
  Fly     3 CCLSDQACEERRISREIDKFLKAEKKKARRELKLLVLGTGESGKTTFIKQMRIIHGKGFLDKERK 67

Human    83 EFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLP 147
            :|...::.|:...::.::.|.:.|.||:|...:.:..|.:.|.|.:        ..||:...||.
  Fly    68 QFTKNVFQNIFMAIQSMISAMDTLRIPYGQQEHSKLADLVKSIDYK--------TVTRLEAPYLN 124

Human   148 AIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFE 212
            ||:.||.|:||:..|:||||:||.:|.:|||:::.::...||..:.||||..|.||..|.||.|.
  Fly   125 AIKTLWKDAGIKECYNRRREYQLTDSTEYFLNDIARIERSDYQATDQDILHVRAPTTNIVEYPFN 189

Human   213 IKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVN 277
            :.....::|||.|||:||::|..||.:||||:|||:.||||..|.|....||:.||..:|..|::
  Fly   190 LDGFLIRLVDVAGQRTERRKWIHCFSNVTSIMFLVAMSEFDLSLAESENDNRMKESKALFHNIIS 254

Human   278 NRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPL 342
            ...|.:.|:||||||.||.::|:....:.|||.|:.|.....:..::|::..|.:...| ..|.:
  Fly   255 FSWFQHSSVILFLNKEDLFKKKILSTHLADYFPEYNGPKKDAKAAREFILYMFTSVNPD-PYKCI 318

Human   343 YHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376
            |.|||.|.|||||:.||..||||||..:|.:..|
  Fly   319 YPHFTVATNTENIKFVFTAVKDTILELHLSETNL 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNA13	NP_006563.2	G_alpha	29..375	CDD:214595	145/345 (42%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	50..63		9/12 (75%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	195..203		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	218..227		4/8 (50%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	287..294		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	347..352		2/4 (50%)
CG17760	NP_001036539.1	G-alpha	34..347	CDD:206639	134/321 (42%)