Protein Alignment GNA13 and Galphao

DIOPT Version :9

• Sequence 1: NP_006563.2
• Gene: GNA13 / 10672
• HGNCID: 4381
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 357
• Identity: 152/357 - (42%)
• Similarity: 219/357 - (61%)
• Gaps: 10/357 - (2%)

Human    17 GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAR 81
            ||..::.|.....:|:.|::.|..:.....:.:|:||||||||||||.:|||:|||...|.....
  Fly     2 GCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDF 66

Human    82 EEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL-QY 145
            :::||.:|||.|:.:..::.|...|.|.:  ::|::..|..|.||     ..|.|.:|..|. :.
  Fly    67 KQYRPVVYSNTIQSLVAILRAMPTLSIQY--SNNERESDAKMVFD-----VCQRMHDTEPFSEEL 124

Human   146 LPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYD 210
            |.|::.||.|:|:|..:.|..|:||.:|.|||||:||:||..||.|::||||..|..|.||.|..
  Fly   125 LAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVH 189

Human   211 FEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETI 275
            |..||:.||:.||||||||||:|..||:.||:|:|.|:.||:||||.||..|||:.|||.:|::|
  Fly   190 FSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSI 254

Human   276 VNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQK 340
            .||:.|::.||||||||.||.|||::...:...|.|:.|... ..:...::...|..|.: ...|
  Fly   255 CNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQE-YGEAAAYIQAQFEAKNK-STSK 317

Human   341 PLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
            .:|.|.|.|.:|.||:.||..|.|.|:.:||:
  Fly   318 EIYCHMTCATDTNNIQFVFDAVTDVIIANNLR 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNA13	NP_006563.2	G_alpha	29..375	CDD:214595	149/345 (43%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	50..63		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	195..203		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	218..227		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	287..294		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	347..352		2/4 (50%)
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	144/322 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830