DRSC/TRiP Functional Genomics Resources

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Protein Alignment CELF1 and URN1

DIOPT Version :10

Sequence 1:NP_001317201.1 Gene:CELF1 / 10658 HGNCID:2549 Length:514 Species:Homo sapiens
Sequence 2:NP_015478.1 Gene:URN1 / 856275 SGDID:S000006356 Length:465 Species:Saccharomyces cerevisiae


Alignment Length:192 Identity:40/192 - (20%)
Similarity:71/192 - (36%) Gaps:48/192 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    70 YEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVED 134
            |..|..:.|.:.|...||....:  ..|.:...:....:::::.|.|..|.   .|..|....:|
Yeast    18 YNKNTKQSRWEKPNLKKGSNLES--NAKESQTERKPTFSLELVNGWHLIIY---NDGTKLYFNDD 77

Human   135 RKLFIGMISKKCTENDIRVMFSSFGQIEECR-ILRGPD--------GLSRGCAFVTFTTRAMAQT 190
            .|.|...||:   |:|.|           || ::...|        |::||     :|.|.....
Yeast    78 SKEFKNDISQ---EDDSR-----------CRSLIESLDKEKLVLLIGVARG-----YTMREEDID 123

Human   191 AIKAMHQAQTMEGCSSPMVVKFADTQKDKEQK----RMAQQLQQQMQQ--ISAASVWGNLAG 246
            .|        :|.|:..:.: |...|.:.|:|    ..|..::..:|:  ....|.:|:.:|
Yeast   124 KI--------LESCNEEIHL-FKRNQDEVERKDEISEEAGDVKSPLQESHTGLVSGYGSSSG 176

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CELF1NP_001317201.1 RRM1_CELF1_2_Bruno 42..125 CDD:410040 10/54 (19%)
RRM2_CELF1_2 134..214 CDD:410042 20/88 (23%)
RRM3_CELF1_2 422..513 CDD:241082
URN1NP_015478.1 PRP40 2..>88 CDD:227435 17/77 (22%)
WW 5..30 CDD:459800 3/11 (27%)
FF 219..263 CDD:426471
Blue background indicates that the domain is not in the aligned region.

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