DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CELF1 and WHI3

DIOPT Version :10

Sequence 1:NP_001317201.1 Gene:CELF1 / 10658 HGNCID:2549 Length:514 Species:Homo sapiens
Sequence 2:NP_014202.1 Gene:WHI3 / 855524 SGDID:S000005141 Length:661 Species:Saccharomyces cerevisiae


Alignment Length:407 Identity:81/407 - (19%)
Similarity:142/407 - (34%) Gaps:118/407 - (28%)


- Green bases have known domain annotations that are detailed below.


Human   195 MHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQL-QQQMQQISAASVWGNLAGLNTLGPQYLALY 258
            :.|.|:.:....|.     ..|:...||...||. |||:......|..|.:.||:: ...:..|.
Yeast   245 LSQQQSQQQQQQPQ-----QPQQHSTQKHSPQQCNQQQVNSSIPLSSQGQVIGLHS-NHSHQDLS 303

Human   259 LQLLQQTASSGNL-----NT-------------------LSSLHP------MGGLNAMQLQNLAA 293
            ::...||:..|..     ||                   :|:..|      .|..:|.|..:...
Yeast   304 VESTIQTSDIGKSFLLRDNTEINEKIWGTSGIPSSINGYMSTPQPSTPTLEWGNTSASQHGSSFF 368

Human   294 LAAAASAA-----QNTPSGTNALT---TSSSPLSVLTSSAGSSP----------SSSSSNSVNPI 340
            |.:|||.|     .||.:..||.:   .|::..:...|::...|          |.:||||:.|.
Yeast   369 LPSAASTAIAPTNSNTSANANASSNNGASNNGANQALSASSQQPMMQIGNTINTSLTSSNSLPPY 433

Human   341 ASLGALQTLAGATAGLNVGSLAGMAALN--------------------------------GGLGS 373
            ..:        ::...::.::...:.:|                                ..|.|
Yeast   434 GLM--------SSQSQHISNMVNTSDMNITPQKQNRFMQQPQPEHMYPVNQSNTPQKVPPARLSS 490

Human   374 SGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQ 438
            |..|:...|| .:|:...:|....:.|.|.       |..:....|....:.|....|::.:||.
Yeast   491 SRNSHKNNST-TSLSSNITGSASISQADLS-------LLARIPPPANPADQNPPCNTLYVGNLPS 547

Human   439 EFGDQDLLQMFMPFGNVVSAKV-FIDKQTNLS------KCFGFVSYDNPVSAQAAIQSMNGFQIG 496
            :..:|:|.|:|.  |.....:: |.:|.|..:      .|  ||.:|:...|..|:..:.|.|:.
Yeast   548 DATEQELRQLFS--GQEGFRRLSFRNKNTTSNGHSHGPMC--FVEFDDVSFATRALAELYGRQLP 608

Human   497 MKRLK----VQLKRSKN 509
            ...:.    ::|..|||
Yeast   609 RSTVSSKGGIRLSFSKN 625

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CELF1NP_001317201.1 RRM1_CELF1_2_Bruno 42..125 CDD:410040
RRM2_CELF1_2 134..214 CDD:410042 3/18 (17%)
RRM3_CELF1_2 422..513 CDD:241082 24/99 (24%)
WHI3NP_014202.1 dRRM_Rrp7p 510..>559 CDD:454777 11/55 (20%)
RRM_scw1_like 536..624 CDD:409691 20/91 (22%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.