Protein Alignment CELF1 and NGR1

DIOPT Version :10

• Sequence 1: NP_001317201.1
• Gene: CELF1 / 10658
• HGNCID: 2549
• Length: 514
• Species: Homo sapiens
• Sequence 2: NP_009771.3
• Gene: NGR1 / 852513
• SGDID: S000000416
• Length: 672
• Species: Saccharomyces cerevisiae
• Alignment Length: 470
• Identity: 90/470 - (19%)
• Similarity: 155/470 - (32%)
• Gaps: 184/470 - (39%)

Human    77 DRSQNPPQSKGCCFVTFYTRKAALEAQNALH-NMKVLPGMHHPIQMKPADSEKN----------- 129
            |.|.......|.|||.|.|:|   :|:.||. |...||..:.|    ..:|:.|
Yeast   119 DPSTTQLHHAGYCFVEFETQK---DAKFALSLNATPLPNFYSP----TTNSQTNPTFKRTFRLNW 176

Human   130 ----------NAVEDRKLFIGMISKKCTENDIRVMFSS-FGQIEECRILRGP-DGLSRGCAFVTF 182
                      .:..:..||:|.:|...||.|:..:|.: |..::..|::..| .|.||...||.|
Yeast   177 ASGATLQSSIPSTPEFSLFVGDLSPTATEADLLSLFQTRFKSVKTVRVMTDPLTGSSRCFGFVRF 241

Human   183 TTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKD-----KEQKRMAQQLQQQMQQISAASVWG 242
            ......:.|:..| ..:..:|  ..:.|.:|..:.:     :||::..||||||.||:...
Yeast   242 GDEDERRRALIEM-SGKWFQG--RALRVAYATPRNNMMLQLQEQQQQQQQLQQQHQQLDQE---- 299

Human   243 NLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPM----GGLNAMQLQNLAALAAAASAAQN 303
                 :..||..:.....|:|..::...||.|.:..||    ||::.|::.:            :
Yeast   300 -----DNNGPLLIKTANNLIQNNSNMLPLNALHNAPPMHLNEGGISNMRVND------------S 347

Human   304 TPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALN 368
            .||.|
Yeast   348 LPSNT------------------------------------------------------------ 352

Human   369 GGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFI 433
                                                 ||.:                |....:|:
Yeast   353 -------------------------------------YNTD----------------PTNTTVFV 364

Human   434 YHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMK 498
            ..|..:..:..|..:|.|||.:::.::     .|...| |||.::..:.|:|:||.:.||.:|..
Yeast   365 GGLVPKTTEFQLRSLFKPFGPILNVRI-----PNGKNC-GFVKFEKRIDAEASIQGLQGFIVGGS 423

Human   499 RLKVQLKR-SKNDSK 512
            .:::...| |.:::|
Yeast   424 PIRLSWGRPSSSNAK 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CELF1	NP_001317201.1	RRM1_CELF1_2_Bruno	42..125	CDD:410040	16/48 (33%)
		RRM2_CELF1_2	134..214	CDD:410042	21/81 (26%)
		RRM3_CELF1_2	422..513	CDD:241082	23/92 (25%)
NGR1	NP_009771.3	RRM1_NGR1_NAM8_like	35..180	CDD:410023	18/67 (27%)
		RRM2_NGR1_NAM8_like	191..270	CDD:410025	21/81 (26%)
		RRM3_NGR1_NAM8_like	359..430	CDD:409782	19/76 (25%)