Protein Alignment CELF1 and GBP2

DIOPT Version :10

• Sequence 1: NP_001317201.1
• Gene: CELF1 / 10658
• HGNCID: 2549
• Length: 514
• Species: Homo sapiens
• Sequence 2: NP_009916.1
• Gene: GBP2 / 850346
• SGDID: S000000517
• Length: 427
• Species: Saccharomyces cerevisiae
• Alignment Length: 398
• Identity: 69/398 - (17%)
• Similarity: 126/398 - (31%)
• Gaps: 102/398 - (25%)

Human   125 DSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQ 189
            |:.|.|.  :..:|:..::..||..|::.:|.:.|::.|..|:.. .|..||...|.||.....|
Yeast   114 DATKRNF--ENSIFVRNLTFDCTPEDLKELFGTVGEVVEADIITS-KGHHRGMGTVEFTKNESVQ 175

Human   190 TAIKAMHQAQTMEGCSSPMVVKF----ADTQKDKEQKRMAQQLQQQMQ----QISAASVWGNLAG 246
            .||.....|..|:   ..::|:.    .:..|:..:|...:::....:    .:..:..|.:|..
Yeast   176 DAISKFDGALFMD---RKLMVRQDNPPPEAAKEFSKKATREEIDNGFEVFIINLPYSMNWQSLKD 237

Human   247 LNTLGPQYLALYLQLLQQTASSGNLNTL-----SSLHPMGGLNAMQLQNLAALAAAASAAQNTPS 306
            :.......|...::|.....|.|..:.:     ..:..:...|.|:::  ..:........|...
Yeast   238 MFKECGHVLRADVELDFNGFSRGFGSVIYPTEDEMIRAIDTFNGMEVE--GRVLEVREGRFNKRK 300

Human   307 GTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGL 371
            ..:........|.   .:.|:.|..:..      |::...:|.|..|.|:|.|.
Yeast   301 NNDRYNQRREDLE---DTRGTEPGLAQD------AAVHIDETAAKFTEGVNPGG----------- 345

Human   372 GSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIY-- 434
                                                                    ..|.|||
Yeast   346 --------------------------------------------------------DRNCFIYCS 354

Human   435 HLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKC-FGFVSYDNPVSAQAAIQSMNGFQIGMK 498
            :||......||..:|.|.|.:.:|:  :..|.|.... ...|.|:|.|.|...||.:|.:..|..
Yeast   355 NLPFSTARSDLFDLFGPIGKINNAE--LKPQENGQPTGVAVVEYENLVDADFCIQKLNNYNYGGC 417

Human   499 RLKVQLKR 506
            .|::...|
Yeast   418 SLQISYAR 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CELF1	NP_001317201.1	RRM1_CELF1_2_Bruno	42..125	CDD:410040	69/398 (17%)
		RRM2_CELF1_2	134..214	CDD:410042	20/83 (24%)
		RRM3_CELF1_2	422..513	CDD:241082	25/88 (28%)
GBP2	NP_009916.1	RRM1_HRB1_GBP2	121..197	CDD:410184	20/79 (25%)
		RRM2_HRB1_GBP2	218..292	CDD:410185	8/75 (11%)
		RRM3_HRB1_GBP2	347..425	CDD:410186	24/79 (30%)