Protein Alignment CELF1 and celf1

DIOPT Version :10

• Sequence 1: NP_001317201.1
• Gene: CELF1 / 10658
• HGNCID: 2549
• Length: 514
• Species: Homo sapiens
• Sequence 2: XP_012816629.1
• Gene: celf1 / 549906
• XenbaseID: XB-GENE-854036
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 536
• Identity: 468/536 - (87%)
• Similarity: 499/536 - (93%)
• Gaps: 24/536 - (4%)

Human     1 MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQ 65
            ||:||||||||||||||||||||||||||||:||||.||.|:||||||||||:||||:|||||||
 Frog     1 MASFKLDFLPEMMVDHCSLNSSPVSKKMNGTMDHPDHPDPDSIKMFVGQVPRSWSEKELRELFEQ 65

Human    66 YGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNN 130
            |||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||
 Frog    66 YGAVYEINVLRDRSQNPPQSKGCCFITFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNN 130

Human   131 -------------AVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTF 182
                         :|||||||:||:||||.|||||.|||.||||||.||||||||:|||||||||
 Frog   131 GGLNTVLYPEHPASVEDRKLFVGMVSKKCNENDIRAMFSQFGQIEESRILRGPDGMSRGCAFVTF 195

Human   183 TTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGL 247
            |||:|||.|||||||||||||||||:||||||||||||||||.|||||||||::|||:|||||||
 Frog   196 TTRSMAQMAIKAMHQAQTMEGCSSPIVVKFADTQKDKEQKRMTQQLQQQMQQLNAASMWGNLAGL 260

Human   248 NTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMG---------GLNAMQLQNLAALAAAASAAQN 303
            ::|.|||||||||||||||||||||:||.|||||         ||||||||||||||||||||||
 Frog   261 SSLAPQYLALYLQLLQQTASSGNLNSLSGLHPMGGEYATGMTSGLNAMQLQNLAALAAAASAAQN 325

Human   304 TPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALN 368
            |||..:||||||||||:|||| ||||||:::::|||:||||||||||||||||||||||||||||
 Frog   326 TPSAGSALTTSSSPLSILTSS-GSSPSSNNNSAVNPMASLGALQTLAGATAGLNVGSLAGMAALN 389

Human   369 GGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFI 433
            |||||| ||||||||||||:|||||||||||||||:||||:||:||.:|||||||||||||||||
 Frog   390 GGLGSS-LSNGTGSTMEALSQAYSGIQQYAAAALPSLYNQSLLSQQGLGAAGSQKEGPEGANLFI 453

Human   434 YHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMK 498
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   454 YHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMK 518

Human   499 RLKVQLKRSKNDSKPY 514
            ||||||||||||||||
 Frog   519 RLKVQLKRSKNDSKPY 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CELF1	NP_001317201.1	RRM1_CELF1_2_Bruno	42..125	CDD:410040	78/82 (95%)
		RRM2_CELF1_2	134..214	CDD:410042	69/79 (87%)
		RRM3_CELF1_2	422..513	CDD:241082	90/90 (100%)
celf1	XP_012816629.1	RRM1_CELF1_2_Bruno	42..125	CDD:410040	78/82 (95%)
		RRM2_CELF1_2	147..227	CDD:410042	69/79 (87%)
		RRM3_CELF1_2	442..533	CDD:241082	90/90 (100%)