Protein Alignment CELF1 and bru3

DIOPT Version :10

• Sequence 1: NP_001317201.1
• Gene: CELF1 / 10658
• HGNCID: 2549
• Length: 514
• Species: Homo sapiens
• Sequence 2: NP_001369050.1
• Gene: bru3 / 39527
• FlyBaseID: FBgn0264001
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 431
• Identity: 181/431 - (41%)
• Similarity: 241/431 - (55%)
• Gaps: 74/431 - (17%)

Human   115 MHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAF 179
            |:..:|:|||::|..:...|||||:||:||:.||:|:|.:|..||.||||.|||||||.|:||||
  Fly    21 MNRALQLKPAENESRSEHLDRKLFVGMLSKQQTEDDVRQIFHPFGTIEECTILRGPDGASKGCAF 85

Human   180 VTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNL 244
            |.|.::..||:||..:|.:|||.|.||.:|||:|||:|:::.:||.|                 :
  Fly    86 VKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRMQQ-----------------M 133

Human   245 AG-LNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGT 308
            || :|.|.|                   ...:...|.|.. |.|.|..|.:||||:|..:..:..
  Fly   134 AGHMNLLNP-------------------FVFNQFSPYGAY-AQQQQQAALMAAAATAPGSAAAYM 178

Human   309 NALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAA----LNG 369
            |.:...::.:....:..|..||..|...  |..::|| .|..|...|....:.|..||    .||
  Fly   179 NPMAALATQIPHGLNGTGQPPSLPSPTM--PNFNMGA-NTPNGQPGGAAAAAAAAAAADGVFTNG 240

Human   370 -------------GLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQ--NLLTQQSIGAA 419
                         .:...||.||..:|::   .|:.|:..:...|.|.:|.|  ..|.......|
  Fly   241 IPQTAFPGHPLHLTIPPQGLPNGDAATLQ---HAFPGLPPFPGVAFPAVYGQFPQALPPPLAAVA 302

Human   420 GSQKE-----------GPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFG 473
            .:|:|           ||||.|||||||||||||.:|:|||:|||||:|:|||||:.||.|||||
  Fly   303 PTQREDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRATNQSKCFG 367

Human   474 FVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY 514
            |||:|||.|||||||:|||||||||||||||||.|:.|:||
  Fly   368 FVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPY 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CELF1	NP_001317201.1	RRM1_CELF1_2_Bruno	42..125	CDD:410040	4/9 (44%)
		RRM2_CELF1_2	134..214	CDD:410042	48/79 (61%)
		RRM3_CELF1_2	422..513	CDD:241082	73/101 (72%)
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	48/79 (61%)
		ELAV_HUD_SF	43..404	CDD:273741	169/403 (42%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	64/77 (83%)