Protein Alignment CELF1 and msa1

DIOPT Version :10

• Sequence 1: NP_001317201.1
• Gene: CELF1 / 10658
• HGNCID: 2549
• Length: 514
• Species: Homo sapiens
• Sequence 2: NP_593715.2
• Gene: msa1 / 2542861
• PomBaseID: SPAC13G7.13C
• Length: 533
• Species: Schizosaccharomyces pombe
• Alignment Length: 511
• Identity: 101/511 - (19%)
• Similarity: 169/511 - (33%)
• Gaps: 149/511 - (29%)

Human    20 NSSPV-SKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDL----RELFEQYGAVYEINVLRDRS 79
            :|:|: |...:|.|:...........:||..:..:.||::|    ::.|:|:|.:..:.||:|..
pombe    55 SSTPIPSSSSSGVLNPSSVRGKPVACLFVASLNSSRSEEELTATVKDYFQQWGPLLHVKVLKDWL 119

Human    80 QNPPQSKGCCFVTFY----TRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIG 140
            |.|     ..||.|.    ..||..||||.     :|.|.|..|:         .|..:|.:.|.
pombe   120 QRP-----YSFVQFQNTDDASKALSEAQNT-----ILDGRHIRIE---------RAKVNRTIRIS 165

Human   141 MISKK--CTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEG 203
            ....:  .|:.||..:...:|::|:  :...||   :....|.|..|..|..|..|:..
pombe   166 SAPHQPYITKKDIDNLLEPYGEVED--VTEIPD---QSAFLVRFVYRDEAIAAYTALKH------ 219

Human   204 CSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASS 268
                                               |.|..|...|.               |..:
pombe   220 -----------------------------------SAWPVLWAENV---------------TYQN 234

Human   269 GNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTP----SGTNALTTSSSPLSVL--TSSAGS 327
            |:.....| .|....||...:.    .:......|||    ......:.||.|.|.:  ::||..
pombe   235 GHYKKKGS-SPFSPPNAHSRRR----KSQGKDQSNTPVIKAPAPIPFSVSSDPPSTMGRSNSAVQ 294

Human   328 SPSSSSSNSVN------PIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEA 386
            |||..:.:.||      |..||.:|.::..:...|.    :|.|.|           .|..:.|.
pombe   295 SPSYFAHSLVNSTEFSTPNESLSSLPSILPSIPSLE----SGKAEL-----------PTDGSFEQ 344

Human   387 LTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHL-PQEFGDQDLLQMFM 450
            .....:....:||...|.                      :..::|:..| |.......|:.:|.
pombe   345 PGYPMNPSMMFAAMPPPI----------------------DPYSIFVGQLDPVNCTHYLLVDLFS 387

Human   451 PFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKR 506
            .:|.|:..|:.   ..:....|.|:.:|:..:|.||:..........|.|:|:.::
pombe   388 KYGKVIDCKII---HQSKKPAFAFLRFDSQQAAYAAVCGKTRSPHQKKPLRVEFRQ 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CELF1	NP_001317201.1	RRM1_CELF1_2_Bruno	42..125	CDD:410040	26/90 (29%)
		RRM2_CELF1_2	134..214	CDD:410042	15/81 (19%)
		RRM3_CELF1_2	422..513	CDD:241082	17/86 (20%)
msa1	NP_593715.2	RRM1_RIM4_like	77..162	CDD:409887	28/103 (27%)
		PABP-1234	79..531	CDD:130689	96/487 (20%)
		RRM2_RIM4_like	362..441	CDD:409888	17/104 (16%)