DRSC/TRiP Functional Genomics Resources

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Protein Alignment CELF1 and dre4

DIOPT Version :10

Sequence 1:NP_001317201.1 Gene:CELF1 / 10658 HGNCID:2549 Length:514 Species:Homo sapiens
Sequence 2:NP_592930.1 Gene:dre4 / 2542176 PomBaseID:SPAC13C5.02 Length:411 Species:Schizosaccharomyces pombe


Alignment Length:220 Identity:45/220 - (20%)
Similarity:80/220 - (36%) Gaps:75/220 - (34%)


- Green bases have known domain annotations that are detailed below.


Human    44 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSK-----GCCFVTFYTRKAALEAQ 103
            |:||.:  .....|:.|:|.:|         |.||    |:.|     ...:|..:|:|    .:
pombe    59 KLFVNE--NAEERKNSRDLRKQ---------LPDR----PKFKKRIPNNDSWVVVFTKK----NR 104

Human   104 NALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFG-----QIEE 163
            ...||:|    .|......|.:..|     |.|:....|.|:.:::..:......|     :|.|
pombe   105 YFFHNLK----SHESYWEPPLEISK-----DLKILRLPIRKQISKDSSQSQNVDSGKTNHEEIHE 160

Human   164 CRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVV------KFADTQKDKEQK 222
            .|.|                     ||.|:   :...:|..|...|:      :.:|.::|:|:.
pombe   161 SRHL---------------------QTEIE---EPSGLEESSEESVLYSEEFYEKSDEEEDEEKS 201

Human   223 RMAQQLQ-------QQMQQISAASV 240
            ..|::|:       .|:||:...:|
pombe   202 HSAEELEFGEEDIMYQLQQLDDETV 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CELF1NP_001317201.1 RRM1_CELF1_2_Bruno 42..125 CDD:410040 20/85 (24%)
RRM2_CELF1_2 134..214 CDD:410042 15/90 (17%)
RRM3_CELF1_2 422..513 CDD:241082
dre4NP_592930.1 WW 4..34 CDD:197736
PRP40 9..>387 CDD:227435 45/220 (20%)
WW 90..120 CDD:197736 7/37 (19%)
FF 241..290 CDD:426471
Blue background indicates that the domain is not in the aligned region.

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