DRSC/TRiP Functional Genomics Resources

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Protein Alignment DMRT2 and dmrt11E

DIOPT Version :10

Sequence 1:NP_870987.2 Gene:DMRT2 / 10655 HGNCID:2935 Length:561 Species:Homo sapiens
Sequence 2:NP_511146.2 Gene:dmrt11E / 32291 FlyBaseID:FBgn0030477 Length:377 Species:Drosophila melanogaster


Alignment Length:399 Identity:119/399 - (29%)
Similarity:159/399 - (39%) Gaps:131/399 - (32%)


- Green bases have known domain annotations that are detailed below.


Human     8 SAAGDWEIDVESLELEEDVCGAPR-STPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGAS 71
            :|.|....|.||..|... |..|. |||.|...|..    .:|:||||   :.....|...|.:|
  Fly    22 AANGRQGTDPESDPLHAR-CVVPHASTPRGRRIPWG----HNDDDDDG---NHLTLPDSLTATSS 78

Human    72 PGMPGQPEQRGGPQPRPPLAP--------QASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRN 128
            .|.          |.....||        ||..:.......|      ...|:|.||||||||||
  Fly    79 CGC----------QCLNVRAPFHILLVDQQARMSKDASVRIC------QRERRLLRTPKCARCRN 127

Human   129 HGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQ--------------------- 172
            |||:||:|||||.||||:|.|.||.|||:|||||||||||||||                     
  Fly   128 HGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATASSTKSTGVTTAS 192

Human   173 -----ATEDKKGLSG-----------------------------KQNNFERKAVYQRQVRA---P 200
                 ::|.:..||.                             :|....:|.:|::::|:   .
  Fly   193 ANNSSSSEGEDSLSSTSPPPAHSHPHSHSHPTSCVSNSSSSSATRQALMAQKRIYKQRLRSLQQS 257

Human   201 SLLAKSILEGYRPIPAETYVGGTFP-LPPPVSDRMRKRRAFADKELENIMLEREYKEREM----- 259
            :|...:.:|.|:.         .|| ...|:.:||||||||||.||.::|      |..:     
  Fly   258 TLHITAAMEEYKQ---------RFPTFSSPLMERMRKRRAFADPELNHVM------EATLGGNAL 307

Human   260 --LETSQAAALFLPNRMVPGPDYNSYKSAYSPSP-----VEPPSKDFCNFLPTCLDLTMQYSGSG 317
              ...:.|||...|        .:..:..|.|.|     ..||:    |...|...:|...:|||
  Fly   308 YFATVAAAAAACAP--------VHQEQHIYHPMPPTIPLTIPPT----NPAMTTPAVTTASTGSG 360

Human   318 NMELISSNV 326
            ....:|.::
  Fly   361 KKPKLSFSI 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DMRT2NP_870987.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..119 30/119 (25%)
DM 119..165 CDD:459924 37/45 (82%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 414..435
dmrt11ENP_511146.2 DM 118..164 CDD:459924 37/45 (82%)
Blue background indicates that the domain is not in the aligned region.

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