Protein Alignment DMRT2 and Dmrt2

DIOPT Version :10

• Sequence 1: NP_870987.2
• Gene: DMRT2 / 10655
• HGNCID: 2935
• Length: 561
• Species: Homo sapiens
• Sequence 2: NP_001101067.1
• Gene: Dmrt2 / 309430
• RGDID: 1309047
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 476/559 - (85%)
• Similarity: 500/559 - (89%)
• Gaps: 4/559 - (0%)

Human     5 QAGSAAGDWEIDVESLELEEDVCGAP-RSTPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEA 68
            ||....|||||||||||||||.||.| |:||..|||..|||  |:|||::..|||||:||:||::
  Rat     4 QAVPGVGDWEIDVESLELEEDGCGTPLRATPQEPSPSTADG--EEDEDEEEEDEDAEDEGEGEDS 66

Human    69 GASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVS 133
            .|||.:||:|||.||..||||.|.||.||.....||...||||||||||||||||||||||||||
  Rat    67 SASPEVPGRPEQPGGLAPRPPPAAQALPAAAVVPERGVTAGGGAEPRKLSRTPKCARCRNHGVVS 131

Human   134 CLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVR 198
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||
  Rat   132 CLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVR 196

Human   199 APSLLAKSILEGYRPI-PAETYVGGTFPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLET 262
            |||||||||||||||: .||||:|||.||||||||||||||||||||||||||||||||||||||
  Rat   197 APSLLAKSILEGYRPMTAAETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLET 261

Human   263 SQAAALFLPNRMVPGPDYNSYKSAYSPSPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVS 327
            ||||||||||||||||:|:|||.|:|||..|.|||||||||||||||||||||||||||||||||
  Rat   262 SQAAALFLPNRMVPGPEYSSYKGAFSPSAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVS 326

Human   328 VATTYRQYPLSSRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQD 392
            |||||||||||||||||||||||||||||||.|||||||||||||||.|||||.|||||||||.|
  Rat   327 VATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGAGWDLKGTRVQDGLSAEHD 391

Human   393 MMPSKLEGSLVLPHTPEIQTTRSDLQGHQAVPERSAFSPPRRNFSPIVDTDSLAAQGHVLTKISK 457
            .||.|.|||||||...|:.|:|:|||.|||||||||||||.||||||||.|.|||||||||||||
  Rat   392 GMPPKPEGSLVLPQLSEVPTSRTDLQAHQAVPERSAFSPPSRNFSPIVDMDCLAAQGHVLTKISK 456

Human   458 ENTRHPLPLRHNPFHSLFQQTLTDKSGPELKTPFVKEAFEETPKKHRECLVKDNQKYTFTIDRCA 522
            ||||:||||:.|||||:||.||.||||||||.||||||||||||||||||||:|.||||||||||
  Rat   457 ENTRYPLPLKRNPFHSVFQPTLNDKSGPELKAPFVKEAFEETPKKHRECLVKENPKYTFTIDRCA 521

Human   523 KDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAITRVSQ 561
            |||||||||||||||||||||||||||||||||:|.|||
  Rat   522 KDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAVTPVSQ 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DMRT2	NP_870987.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..119		73/114 (64%)
		DM	119..165	CDD:459924	45/45 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	414..435		17/20 (85%)
Dmrt2	NP_001101067.1	DM	117..163	CDD:459924	45/45 (100%)