Protein Alignment DMRT2 and dmrt2

DIOPT Version :10

• Sequence 1: NP_870987.2
• Gene: DMRT2 / 10655
• HGNCID: 2935
• Length: 561
• Species: Homo sapiens
• Sequence 2: NP_001093726.1
• Gene: dmrt2 / 100101749
• XenbaseID: XB-GENE-876152
• Length: 528
• Species: Xenopus tropicalis
• Alignment Length: 559
• Identity: 337/559 - (60%)
• Similarity: 390/559 - (69%)
• Gaps: 62/559 - (11%)

Human     8 SAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCE----DDEDDDGVDEDAEEEGDGEEA 68
            |.|||.||||||||||.|  |.|..             |.    |:||:   ||:.:|..||
 Frog    27 SLAGDSEIDVESLELEGD--GQPEL-------------CRARHLDEEDE---DEEEQEGADG--- 70

Human    69 GASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVS 133
                                      :|...|.:::....||  |.|||||||||||||||||||
 Frog    71 --------------------------APVSKGEQQKANEKGG--EQRKLSRTPKCARCRNHGVVS 107

Human   134 CLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVR 198
            ||||||||||||||||||||||||||||||||||||||||||||||||.|.:..|||.||||.:|
 Frog   108 CLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSAKPSIAERKPVYQRHIR 172

Human   199 APSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETS 263
            .||||||||||||||:..::|:|.:.|||..|||||||||||||||||:||||||:|||||||.:
 Frog   173 PPSLLAKSILEGYRPVQTDSYLGTSPPLPAQVSDRMRKRRAFADKELEHIMLEREFKEREMLEAT 237

Human   264 QAAALFLPNRMVPGPDYNSYKSAYSPSPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSV 328
            |||.||||||||...:|||||:||.|...:.|:||||||||||||||||||||||||||||||||
 Frog   238 QAAGLFLPNRMVHAAEYNSYKAAYGPPQADVPNKDFCNFLPTCLDLTMQYSGSGNMELISSNVSV 302

Human   329 ATTYRQYPLSSRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQDM 393
            ||||||||:.||||||||.|||||.|||||||||| |::||||||.:||.|...|.:...:|.|:
 Frog   303 ATTYRQYPVPSRFLVWPKTGPISDALLYQQCLLNA-TAMQALKPGPNWDSKSNPVSECQPSEHDL 366

Human   394 M-PSKLEGSLVLPHTPEIQTTRSDLQGHQAVPERSAFSPPRRNFSPIVDTDSLAAQGHVLTKISK 457
            : |||::..::.|     |.....|....|  ||||||||:|||..|...|.|:||..::.||||
 Frog   367 LAPSKIDNPILHP-----QNDYGSLPQDNA--ERSAFSPPKRNFPLISSKDHLSAQDSLMNKISK 424

Human   458 ENTRHPLPLRHNPFHSLFQQTLTDKSGPELKTPFVKEAFEETPKKHRECLVKDNQKYTFTIDRCA 522
            |.|:.|..|::||||:|.||...:||..:||.|.||:.:||..||.||...|:||||.||.||..
 Frog   425 EVTKQPHSLKYNPFHALLQQAHLEKSLEDLKPPCVKDLYEEPAKKFREYPSKENQKYKFTFDRHN 489

Human   523 KDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAITRVSQ 561
            ||.|:..:.||||:|:|||.|||||||||||:.:.|.||
 Frog   490 KDFFLGNESGTKLTVSEPLPFSVESILKRPSTTVKRSSQ 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DMRT2	NP_870987.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..119		34/114 (30%)
		DM	119..165	CDD:459924	45/45 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	414..435		10/20 (50%)
dmrt2	NP_001093726.1	DM	93..139	CDD:459924	45/45 (100%)