Protein Alignment MTX2 and CG8004

DIOPT Version :10

• Sequence 1: NP_006545.1
• Gene: MTX2 / 10651
• HGNCID: 7506
• Length: 263
• Species: Homo sapiens
• Sequence 2: NP_649161.1
• Gene: CG8004 / 40178
• FlyBaseID: FBgn0036920
• Length: 269
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 112/261 - (42%)
• Similarity: 166/261 - (63%)
• Gaps: 11/261 - (4%)

Human     8 FVSQI-----AAAEPWPENATLYQQLKGEQILLSDNAASLAVQAFLQMCNLPIKVVCRANAEYMS 67
            ::||:     .:||||||:|||||..:.|||||.:||:.|||:|:|:|||||..:...||||:||
  Fly     5 YLSQLITADKLSAEPWPEDATLYQPYEAEQILLPENASCLAVKAYLKMCNLPFLIRSCANAEHMS 69

Human    68 PSG---KVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLEEVQKAEMKAYMELVNNMLLTAELYL 129
            |.|   |:|||..|..:.:|..|||.||:.|..::....:|.:||:|:.|:.||.|:...||||:
  Fly    70 PGGRMTKLPFIRAGAFIFAEFEPIVNFVEQKELAIGSWQDEDEKADMRTYVSLVENIFTMAELYI 134

Human   130 QWCDEATVGEITHARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGKKTLDQVLEDVDQCCQALS 194
            .:.:|....|:|..|.|..:||||||:..|.|:....|.:|...|....:|.|::.|.:||:.|.
  Fly   135 SFKNERVYKEVTAPRNGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVIDKVAKCCETLE 199

Human   195 QRLGTQ---PYFFNKQPTELDALVFGHLYTILTTQLTNDELSEKVKNYSNLLAFCRRIEQHYFED 256
            .:|...   |:|:..||.||||:.||||::||||.|.|..|::.|:.:.:|:.|||.:::.||:.
  Fly   200 YKLKESPETPFFYGDQPCELDAIAFGHLFSILTTTLPNMALAQTVQKFQHLVEFCRFVDEKYFQT 264

Human   257 R 257
            |
  Fly   265 R 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTX2	NP_006545.1	GST_N_Metaxin2	22..95	CDD:239377	41/75 (55%)
		GST_C_Metaxin2	125..250	CDD:198320	51/127 (40%)
CG8004	NP_649161.1	GST_N_Metaxin2	24..100	CDD:239377	41/75 (55%)
		GST_C_Metaxin2	130..258	CDD:198320	51/127 (40%)