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Protein Alignment IGF2BP3 and PBP2

DIOPT Version :10

Sequence 1:	XP_047275738.1	Gene:	IGF2BP3 / 10643	HGNCID:	28868	Length:	634	Species:	Homo sapiens
Sequence 2:	NP_009792.3	Gene:	PBP2 / 852533	SGDID:	S000000437	Length:	413	Species:	Saccharomyces cerevisiae

Alignment Length:	440	Identity:	94/440 - (21%)
Similarity:	172/440 - (39%)	Gaps:	108/440 - (24%)

- Green bases have known domain annotations that are detailed below.

Human   210 PDEMAAQQNPLQQPRGR----------------RGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVP 258
            |..:....|.|::.:|.                :.......:...||.:|    |.|:.||:|..
Yeast    14 PTTVLVSPNTLKRKKGEDTSEEQLEAEIKRVALKDADSHSDNDHDSPDNV----PSDVHLRMLCL 74

Human   259 TQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKE- 322
            .:....|:|.:||||..|..:|.::|::..... |..|:.:.:..|.:..:.|...|:..:.:|
Yeast    75 VKHASLIVGHKGATISRIKSETSARINISNNIR-GVPERIVYVRGTCDDVAKAYGMIVRALLEEH 138

Human   323 -----AQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTI 382
                 .:||    ||.:.:|..::.:|.:|||.|..|::||..:..|:..|| .:|.|.| :|.:
Yeast   139 GNEDNGEDI----EISINLLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASP-NQLLLSN-DRIL 197

Human   383 TVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSA 447
            |:.|..:....|...|.:.:          :|.|.. .|..|:.....:.||
Yeast   198 TINGVPDAIHIATFYISQTL----------LNFQME-SPQKNVKRSIYYQPT------------- 238

Human   448 MTPPYPQF-----EQSETETV-----HLFIPA---LSVGAIIGKQGQHIKQLS--------RFAG 491
                  ||     :.|:..|:     |.:.|:   ||.     |..:::...|        ::..
Yeast   239 ------QFNSVLIDHSQPNTIFHQRNHQYHPSDKLLSY-----KPNKNLPISSTLLSMATPQYTT 292

Human   492 ASIKIAPAEAPDAKV-RMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAG 555
            ||:..|.|..|:..: .:.::.||..:.......:...:::|.|:..|              ..|
Yeast   293 ASVANATAFQPNFVIPNVTVLDGPVISPAPGNHLLMNFVQQEIFIDEK--------------FVG 343

Human   556 RVIGKGGKTVNELQNLSSAEVVVPRDQTPDE-NDQVVVKITGHFYACQVA 604
            .||||.||.:|.::..:...:::   |.|.| :.:..:.|.|.|.|.|.|
Yeast   344 NVIGKDGKHINSVKESTGCSIII---QDPVEGSSERRLTIRGTFMASQAA 390

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.