Protein Alignment IGF2BP3 and Igf2bp3

DIOPT Version :10

• Sequence 1: XP_047275738.1
• Gene: IGF2BP3 / 10643
• HGNCID: 28868
• Length: 634
• Species: Homo sapiens
• Sequence 2: NP_076159.3
• Gene: Igf2bp3 / 140488
• MGIID: 1890359
• Length: 579
• Species: Mus musculus
• Alignment Length: 535
• Identity: 511/535 - (95%)
• Similarity: 517/535 - (96%)
• Gaps: 4/535 - (0%)

Human   104 PGPGAGLRP----PGKIELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVES 164
            |..|..|:.    .||:||||||:|||||||||||||||||||||||||||||||||||||||||
Mouse    45 PDEGWALKAIEALSGKMELHGKPMEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVES 109

Human   165 CEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGL 229
            ||||||||||||||||||||||||||||||||||||||||||||||||.||||||..|.|||||.
Mouse   110 CEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDETAAQQNPSPQLRGRRGP 174

Human   230 GQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA 294
            ||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||.||
Mouse   175 GQRGSSRQASPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENTGA 239

Human   295 AEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQ 359
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   240 AEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQ 304

Human   360 DTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLN 424
            |||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
Mouse   305 DTDTKITISPLQELTLYNPERTITVKGSVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLN 369

Human   425 LNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRF 489
            ||||||||||||||||||||||.:|||||||||||||||||||||||||||||||||||||||||
Mouse   370 LNALGLFPPTSGMPPPTSGPPSTLTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRF 434

Human   490 AGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAA 554
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   435 AGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAA 499

Human   555 GRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQ 619
            |||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   500 GRVIGKGGKTVNELQSLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQ 564

Human   620 QQKALQSGPPQSRRK 634
            |||||||||||||||
Mouse   565 QQKALQSGPPQSRRK 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IGF2BP3	XP_047275738.1	RRM_SF	<114..132	CDD:473069	15/17 (88%)
		RRM2_IGF2BP3	136..211	CDD:410039	74/74 (100%)
		KH-I_IGF2BP3_rpt1	252..327	CDD:411920	73/74 (99%)
		KH-I	330..424	CDD:469614	92/93 (99%)
		KH-I_IGF2BP3_rpt3	457..534	CDD:411926	76/76 (100%)
		KH-I_IGF2BP1_rpt4	542..617	CDD:411927	73/74 (99%)
Igf2bp3	NP_076159.3	RRM_SF	1..77	CDD:473069	18/31 (58%)
		RRM2_IGF2BP3	81..156	CDD:410039	74/74 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..192		27/33 (82%)
		KH-I_IGF2BP3_rpt1	197..272	CDD:411920	73/74 (99%)
		KH-I	275..369	CDD:469614	92/93 (99%)
		KH-I_IGF2BP3_rpt3	402..479	CDD:411926	76/76 (100%)
		KH-I	487..562	CDD:469614	73/74 (99%)